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SPDR S&P Biotech ETF
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Overview Fund Activity

632 hedge funds and large institutions have $7.94B invested in SPDR S&P Biotech ETF in 2021 Q3 according to their latest regulatory filings, with 55 funds opening new positions, 224 increasing their positions, 184 reducing their positions, and 72 closing their positions.

Holders
632
Holders Change
-28
Holders Change %
-4.24%
% of All Funds
11.1%
Holding in Top 10
20
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+17.65%
% of All Funds
0.35%
New
55
Increased
224
Reduced
184
Closed
72
Calls
$1.5B
Puts
$3.28B
Net Calls
-$1.77B
Net Calls Change
-$796M

Top Buyers

1
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
1
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$617M
2
Jane Street
2
Jane Street
New York
$127M
3
Goldman Sachs
3
Goldman Sachs
New York
$862M
4
Thrivent Financial for Lutherans
4
Thrivent Financial for Lutherans
Minnesota
$82.8M
5
PF
5
Phoenix Financial
Israel
$71.4M

Top Sellers

1
Citigroup
1
Citigroup
New York
$332M
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$332M
3
Toronto Dominion Bank
3
Toronto Dominion Bank
Ontario, Canada
$637M
4
Morgan Stanley
4
Morgan Stanley
New York
$417M
5
Canada Pension Plan Investment Board
5
Canada Pension Plan Investment Board
Ontario, Canada
$50.3M
Name Market Value Shares Shares
Change 		Shares
Change %
Goldman Sachs
1
Goldman Sachs
New York
$862M 6,854,054 +804,759 +13%
Bank of America
2
Bank of America
North Carolina
$755M 6,003,649 -223,786 -4%
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$655M 5,214,207 -590,385 -10%
Toronto Dominion Bank
4
Toronto Dominion Bank
Ontario, Canada
$637M 5,069,535 -1,305,665 -20%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
5
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$617M 4,905,000 +1,271,000 +35%
Morgan Stanley
6
Morgan Stanley
New York
$417M 3,316,128 -648,449 -16%
Citigroup
7
Citigroup
New York
$332M 2,643,333 -3,070,303 -54%
JPMorgan Chase & Co
8
JPMorgan Chase & Co
New York
$332M 2,640,450 -1,912,098 -42%
Barclays
9
Barclays
United Kingdom
$236M 1,874,123 -41,992 -2%
UBS Group
10
UBS Group
Switzerland
$185M 1,469,803 -541,065 -27%
O
11
OrbiMed
New York
$134M 1,065,700 +130,000 +14%
Jane Street
12
Jane Street
New York
$127M 1,008,287 +823,149 +445%
Wells Fargo
13
Wells Fargo
California
$119M 947,408 -15,166 -2%
Thrivent Financial for Lutherans
14
Thrivent Financial for Lutherans
Minnesota
$82.8M 658,645 +658,645 New
CI
15
Clal Insurance
Israel
$71.8M 571,350 +111,000 +24%
PF
16
Phoenix Financial
Israel
$71.4M 567,650 +567,650 New
Bank Julius Baer & Co
17
Bank Julius Baer & Co
Switzerland
$70.8M 563,545 +127,688 +29%
LPL Financial
18
LPL Financial
California
$67.4M 535,963 -42,302 -7%
Royal Bank of Canada
19
Royal Bank of Canada
Ontario, Canada
$52.3M 416,137 +47,516 +13%
Canada Pension Plan Investment Board
20
Canada Pension Plan Investment Board
Ontario, Canada
$50.3M 400,000 -600,000 -60%
CAC
21
Cowen and Company
New York
$50.3M 400,000 -48,702 -11%
JG
22
Jefferies Group
New York
$41.5M 330,250 – –
Millennium Management
23
Millennium Management
New York
$41.4M 329,052 +21,884 +7%
AI
24
Atom Investors
Texas
$39.7M 315,854 +53,021 +20%
Ensign Peak Advisors
25
Ensign Peak Advisors
Utah
$37.7M 300,000 +300,000 New
1
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