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State Street SPDR S&P Biotech ETF

656 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 100 funds opening new positions, 151 increasing their positions, 243 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

59% more first-time investments, than exits

New positions opened: 100 | Existing positions closed: 63

20% more funds holding in top 10

Funds holding in top 10: 1518 (+3)

16% more capital invested

Capital invested by funds: $10.7B → $12.4B (+$1.69B)

14.41% more ownership

Funds ownership: 200.2%214.61% (+14%)

5% more funds holding

Funds holding: 625656 (+31)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 151 | Existing positions reduced: 243

Holders
656
Holders Change
+31
Holders Change %
+4.96%
% of All Funds
8.61%
Holding in Top 10
18
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+20%
% of All Funds
0.24%
New
100
Increased
151
Reduced
243
Closed
63
Calls
$2.38B
Puts
$3.15B
Net Calls
-$772M
Net Calls Change
+$5.45M
Name Holding Trade Value Shares
Change
Change in
Stake
Goldman Sachs
1
Goldman Sachs
New York
$2.28B +$418M +4,636,025 +26%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.39B +$152M +1,689,000 +14%
JP Morgan Chase
3
JP Morgan Chase
New York
$1.36B +$261M +2,900,633 +27%
Citigroup
4
Citigroup
New York
$1.09B -$168M -1,862,849 -15%
Morgan Stanley
5
Morgan Stanley
New York
$1.06B -$72.7M -807,651 -7%
Bank of America
6
Bank of America
North Carolina
$942M +$248M +2,750,350 +41%
BNP Paribas Financial Markets
7
BNP Paribas Financial Markets
France
$598M -$148M -1,645,780 -22%
Wells Fargo
8
Wells Fargo
California
$279M -$13.2M -146,099 -5%
UBS Group
9
UBS Group
Switzerland
$241M -$154M -1,710,420 -42%
Barclays
10
Barclays
United Kingdom
$201M +$134M +1,487,139 +288%
Canada Pension Plan Investment Board
11
Canada Pension Plan Investment Board
Ontario, Canada
$176M
Bessemer Group
12
Bessemer Group
New Jersey
$164M +$12.5M +138,322 +9%
JFG
13
Jefferies Financial Group
New York
$151M +$6.68M +74,191 +5%
MASUI
14
MIRAE ASSET SECURITIES (USA) INC.
New York
$150M
Ameriprise
15
Ameriprise
Minnesota
$123M +$31.8M +353,351 +40%
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$116M +$87.5M +971,838 +534%
ERSOT
17
Employees Retirement System of Texas
Texas
$74M -$10.4M -115,100 -13%
LPL Financial
18
LPL Financial
California
$68.3M +$6.94M +77,048 +13%
MIH
19
Meitav Investment House
Israel
$68.2M +$25.4M +281,602 +70%
GF
20
Greenhouse Funds
Maryland
$67.7M +$8.67M +96,308 +17%
Twin Tree Management
21
Twin Tree Management
Texas
$66.8M +$26.9M +298,482 +81%
HSBC Holdings
22
HSBC Holdings
United Kingdom
$59M -$10.7M -118,565 -17%
GAMH
23
Greenwoods Asset Management (HK)
Hong Kong
$55.6M +$50M +555,015 New
N
24
Natixis
France
$49.9M -$190K -2,104 -0.4%
Royal Bank of Canada
25
Royal Bank of Canada
Ontario, Canada
$44.3M -$982K -10,907 -2%