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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

613 hedge funds and large institutions have $9.73B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 270 reducing their positions, and 102 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
613
Holders Change
-59
Holders Change %
-8.78%
% of All Funds
8.23%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
270
Closed
102
Calls
$1.47B
Puts
$2.24B
Net Calls
-$777M
Net Calls Change
+$309M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$1.5B
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.01B
3
Citigroup
3
Citigroup
New York
$1.06B
4
Wells Fargo
4
Wells Fargo
California
$243M
5
JFG
5
Jefferies Financial Group
New York
$119M

Top Sellers

1
DFG
1
Demars Financial Group
Washington
$247K
2
UBS Group
2
UBS Group
Switzerland
$341M
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$631M
4
HIIFS
4
Harel Insurance Investments & Financial Services
Israel
$0
5
Squarepoint
5
Squarepoint
New York
$39.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
MA
201
Mutual Advisors
Nebraska
$1.36M -$66K -753 -5%
GA
202
GFS Advisors
Texas
$1.34M – – –
BPC
203
Bearing Point Capital
Minnesota
$1.32M -$3.59M -43,274 -73%
Truist Financial
204
Truist Financial
North Carolina
$1.32M -$432K -5,213 -25%
LWM
205
LJI Wealth Management
Indiana
$1.3M +$72.2K +871 +6%
BCM
206
Brookstone Capital Management
Illinois
$1.29M +$1.04M +12,489 +408%
PCM
207
Prelude Capital Management
New York
$1.24M +$81.8K +986 +7%
SCA
208
STALEY CAPITAL ADVISERS
Pennsylvania
$1.19M -$141K -1,700 -11%
AMI
209
Amica Mutual Insurance
Rhode Island
$1.17M – – –
MIA
210
MeadowBrook Investment Advisors
Michigan
$1.17M -$22.4K -270 -2%
PMA
211
Prudent Man Advisors
Illinois
$1.16M +$183K +2,211 +19%
NL
212
NVWM LLC
Pennsylvania
$1.14M +$42.6K +514 +4%
EIP
213
Easterly Investment Partners
Massachusetts
$1.12M -$815K -9,825 -42%
QOP
214
Quinn Opportunity Partners
Virginia
$1.12M +$1.12M +13,500 New
EWA
215
Evolution Wealth Advisors
Florida
$1.11M -$94.5K -1,139 -8%
WJWM
216
Williams Jones Wealth Management
New York
$1.11M -$3.61M -43,579 -77%
PI
217
PFG Investments
New York
$1.11M -$111K -1,337 -9%
SPIA
218
Steward Partners Investment Advisory
New York
$1.1M -$68.2K -822 -6%
MIC
219
Meridian Investment Counsel
California
$1.1M +$39K +470 +4%
Carson Wealth (CWM LLC)
220
Carson Wealth (CWM LLC)
Nebraska
$1.09M -$290K -3,494 -21%
Vontobel Holding
221
Vontobel Holding
Switzerland
$1.09M -$651K -7,846 -37%
SG
222
Sharper & Granite
California
$1.07M -$105K -1,235 -9%
Cerity Partners
223
Cerity Partners
New York
$1.06M -$480K -5,793 -31%
PF
224
Phoenix Financial
Israel
$1.06M -$22M -265,255 -95%
CIA
225
Choate Investment Advisors
Massachusetts
$1.04M – – –
7 8
9
10 11