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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

613 hedge funds and large institutions have $9.73B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 270 reducing their positions, and 102 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
613
Holders Change
-59
Holders Change %
-8.78%
% of All Funds
8.23%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
270
Closed
102
Calls
$1.47B
Puts
$2.24B
Net Calls
-$777M
Net Calls Change
+$309M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$1.5B
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.01B
3
Citigroup
3
Citigroup
New York
$1.06B
4
Wells Fargo
4
Wells Fargo
California
$243M
5
JFG
5
Jefferies Financial Group
New York
$119M

Top Sellers

1
DFG
1
Demars Financial Group
Washington
$247K
2
UBS Group
2
UBS Group
Switzerland
$341M
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$631M
4
HIIFS
4
Harel Insurance Investments & Financial Services
Israel
$0
5
Squarepoint
5
Squarepoint
New York
$39.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
CIBC Private Wealth Group
176
CIBC Private Wealth Group
Georgia
$1.69M -$49.8K -600 -3%
CAM
177
Crown Advisors Management
California
$1.66M – – –
Capital Fund Management (CFM)
178
Capital Fund Management (CFM)
France
$1.65M -$13.8M -166,055 -89%
AWA
179
Arete Wealth Advisors
Illinois
$1.63M -$23.1K -279 -1%
VAM
180
Verity Asset Management
North Carolina
$1.63M -$10.9K -132 -0.7%
HWA
181
Hillcrest Wealth Advisors
New Jersey
$1.61M -$187K -2,260 -10%
VWA
182
Visionary Wealth Advisors
Illinois
$1.57M +$586K +7,068 +59%
IMC Chicago
183
IMC Chicago
Illinois
$1.55M -$4.6M -55,522 -75%
CIBC World Market
184
CIBC World Market
Ontario, Canada
$1.54M -$2.27M -27,316 -60%
5SA
185
5th Street Advisors
Connecticut
$1.5M +$73.1K +882 +5%
AIP
186
Ameritas Investment Partners
Nebraska
$1.49M – – –
SSA
187
Schonfeld Strategic Advisors
New York
$1.49M +$1.49M +17,926 New
BP
188
Ballentine Partners
Massachusetts
$1.47M – – –
DWP
189
Daymark Wealth Partners
Ohio
$1.47M – – –
PFA
190
Pettinga Financial Advisors
Indiana
$1.47M -$905K -10,915 -38%
TSS
191
Two Sigma Securities
New York
$1.45M +$411K +4,960 +39%
FHA
192
Flagship Harbor Advisors
Massachusetts
$1.44M -$20K -241 -1%
Victory Capital Management
193
Victory Capital Management
Texas
$1.43M +$1.43M +17,249 New
SC
194
Syon Capital
California
$1.41M -$18.2K -219 -1%
BFO
195
Biltmore Family Office
North Carolina
$1.4M -$43.6K -526 -3%
RFWA
196
RPg Family Wealth Advisory
Massachusetts
$1.38M -$278K -3,355 -17%
Capstone Investment Advisors
197
Capstone Investment Advisors
New York
$1.37M +$936K +11,287 +214%
Jones Financial Companies
198
Jones Financial Companies
Missouri
$1.37M -$195K -2,353 -12%
BA
199
Bristlecone Advisors
Washington
$1.36M -$618K -7,447 -31%
AC
200
ASB Consultores
Florida
$1.36M – – –
6 7
8
9 10