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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

613 hedge funds and large institutions have $9.73B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 270 reducing their positions, and 102 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
613
Holders Change
-59
Holders Change %
-8.78%
% of All Funds
8.23%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
270
Closed
102
Calls
$1.47B
Puts
$2.24B
Net Calls
-$777M
Net Calls Change
+$309M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$1.5B
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.01B
3
Citigroup
3
Citigroup
New York
$1.06B
4
Wells Fargo
4
Wells Fargo
California
$243M
5
JFG
5
Jefferies Financial Group
New York
$119M

Top Sellers

1
DFG
1
Demars Financial Group
Washington
$247K
2
UBS Group
2
UBS Group
Switzerland
$341M
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$631M
4
HIIFS
4
Harel Insurance Investments & Financial Services
Israel
$0
5
Squarepoint
5
Squarepoint
New York
$39.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
CA
126
Continental Advisors
Utah
$3.04M +$871K +10,500 +40%
FT
127
Fiduciary Trust
Massachusetts
$3.04M -$377K -4,549 -11%
JWCA
128
J.W. Cole Advisors
Florida
$3.03M +$44.8K +540 +1%
BPWM
129
BCS Private Wealth Management
New Jersey
$3M +$3M +36,126 New
MHFA
130
Mission Hills Financial Advisory
California
$2.96M -$55.4K -668 -2%
TCA
131
Transcend Capital Advisors
New Jersey
$2.83M -$1.2M -14,486 -30%
IWM
132
IHT Wealth Management
Illinois
$2.82M -$746K -8,998 -21%
Citadel Advisors
133
Citadel Advisors
Florida
$2.65M -$11M -132,622 -81%
IWC
134
Integrated Wealth Concepts
Massachusetts
$2.61M -$289K -3,489 -10%
AWMNY
135
Arcadia Wealth Management (New York)
New York
$2.6M -$37.3K -450 -1%
Creative Planning
136
Creative Planning
Kansas
$2.6M +$28.9K +348 +1%
CICI
137
Capital Investment Counsel Inc
North Carolina
$2.59M +$2.57M +30,985 +15,115%
BPC
138
Banque Pictet & Cie
Switzerland
$2.57M -$247K -2,973 -9%
Focus Partners Wealth
139
Focus Partners Wealth
Massachusetts
$2.55M -$188K -2,264 -7%
National Bank of Canada
140
National Bank of Canada
Quebec, Canada
$2.53M +$1.73M +20,854 +217%
CBA
141
Coastal Bridge Advisors
Connecticut
$2.52M +$2.52M +30,399 New
MCM
142
Massar Capital Management
Connecticut
$2.49M +$498K +6,000 +25%
AI
143
ArchPoint Investors
Florida
$2.48M – – –
AUB
144
Atlantic Union Bankshares
Virginia
$2.47M +$2.47M +29,829 New
NFG
145
Nations Financial Group
Iowa
$2.43M -$20.9K -252 -0.9%
GP
146
Greenline Partners
New York
$2.38M – – –
CCA
147
Conservest Capital Advisors
Pennsylvania
$2.38M -$241K -2,910 -9%
DCM
148
Dimension Capital Management
Florida
$2.32M – – –
ACP
149
Argyle Capital Partners
California
$2.15M -$89.6K -1,081 -4%
Mariner
150
Mariner
Kansas
$2.14M +$43.5K +524 +2%
4 5
6
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