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State Street SPDR S&P Biotech ETF

641 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 97 funds opening new positions, 148 increasing their positions, 238 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

more ownership

Funds ownership:

4% more funds holding

Funds holding: 618641 (+23)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 148 | Existing positions reduced: 238

Holders
641
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Marshall Wace
126
Marshall Wace
United Kingdom
$3.44M
TCA
127
Transcend Capital Advisors
New Jersey
$3.41M
SAM
128
Sectoral Asset Management
Quebec, Canada
$3.41M
Man Group
129
Man Group
United Kingdom
$3.34M
Franklin Resources
130
Franklin Resources
California
$3.3M
Walleye Trading
131
Walleye Trading
New York
$3.13M
CICI
132
Capital Investment Counsel Inc
North Carolina
$3.13M
AWMNY
133
Arcadia Wealth Management (New York)
New York
$3.05M
Focus Partners Wealth
134
Focus Partners Wealth
Massachusetts
$3.04M
BPA
135
Beacon Pointe Advisors
California
$3.02M
MCM
136
Massar Capital Management
Connecticut
$3.01M
AI
137
ArchPoint Investors
Florida
$2.99M
QL
138
Quarry LP
New York
$2.95M
CCA
139
Conservest Capital Advisors
Pennsylvania
$2.92M
GP
140
Greenline Partners
New York
$2.88M
SCP
141
Stamos Capital Partners
California
$2.86M
DCM
142
Dimension Capital Management
Florida
$2.77M
DAM
143
DLD Asset Management
New York
$2.72M
AUB
144
Atlantic Union Bankshares
Virginia
$2.64M
IWC
145
Integrated Wealth Concepts
Massachusetts
$2.6M
P
146
&Partners
Tennessee
$2.55M
HCP
147
Holt Capital Partners
Texas
$2.54M
GHC
148
Great Hill Capital
New York
$2.52M
HCMT
149
Highland Capital Management (Tennessee)
Tennessee
$2.47M
PA
150
Parallel Advisors
California
$2.45M