XBI icon

SPDR S&P Biotech ETF
XBI

Overview Fund Activity

611 hedge funds and large institutions have $9.72B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 268 reducing their positions, and 102 closing their positions.

Holders
611
Holders Change
-61
Holders Change %
-9.08%
% of All Funds
8.21%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
268
Closed
102
Calls
$1.14B
Puts
$1.97B
Net Calls
-$834M
Net Calls Change
+$252M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$1.5B
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.01B
3
Citigroup
3
Citigroup
New York
$1.06B
4
Wells Fargo
4
Wells Fargo
California
$243M
5
JFG
5
Jefferies Financial Group
New York
$119M

Top Sellers

1
DFG
1
Demars Financial Group
Washington
$247K
2
UBS Group
2
UBS Group
Switzerland
$341M
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$631M
4
HIIFS
4
Harel Insurance Investments & Financial Services
Israel
$0
5
Squarepoint
5
Squarepoint
New York
$39.2M
Name Market Value Shares Shares
Change 		Shares
Change %
PIA
101
Petredis Investment Advisors
Pennsylvania
$4.58M 55,170 +503 +0.9%
LK
102
Lumbard & Kellner
New Hampshire
$4.57M 55,089 -21,806 -28%
FC
103
Fulcrum Capital
Washington
$4.56M 54,960 +3,122 +6%
Cambridge Investment Research Advisors
104
Cambridge Investment Research Advisors
Iowa
$4.37M 52,726 -6,816 -11%
TS
105
Tamar Securities
California
$4.28M 51,627 +2,544 +5%
CDIEC
106
Crédit Industriel et Commercial
France
$4.21M 50,800 +3,322 +7%
GCM
107
Graham Capital Management
Connecticut
$4.15M 50,000 +50,000 New
CIC
108
Carnegie Investment Counsel
Ohio
$4.11M 49,615 -1,830 -4%
IHL
109
Investment House LLC
California
$4.11M 49,515 +45,365 +1,093%
Renaissance Technologies
110
Renaissance Technologies
New York
$4.05M 48,800 +48,800 New
Janney Montgomery Scott
111
Janney Montgomery Scott
Pennsylvania
$3.96M 47,720 -19,991 -30%
QT
112
Quantbot Technologies
New York
$3.95M 47,650 +4,311 +10%
Franklin Resources
113
Franklin Resources
California
$3.86M 46,570 -8,825 -16%
AFA
114
American Financial Advisors
Georgia
$3.82M 46,061 -1,366 -3%
Baird Financial Group
115
Baird Financial Group
Wisconsin
$3.81M 45,925 -4,766 -9%
PNC Financial Services Group
116
PNC Financial Services Group
Pennsylvania
$3.63M 43,822 -22,656 -34%
MS
117
Maven Securities
Jersey
$3.49M 42,117 +23,011 +120%
BPIM
118
Brant Point Investment Management
New York
$3.42M 41,242 -7,992 -16%
SCP
119
Stamos Capital Partners
California
$3.33M 40,164 +12,978 +48%
SC
120
Scotia Capital
Ontario, Canada
$3.23M 38,969 +1,450 +4%
MCM
121
MAI Capital Management
Ohio
$3.2M 38,620 +31,995 +483%
LBA
122
Letko, Brosseau & Associates
Quebec, Canada
$3.18M 38,325 -1,675 -4%
BBVA
123
Banco Bilbao Vizcaya Argentaria
Spain
$3.17M 38,072 -18,775 -33%
PAG
124
Private Advisor Group
New Jersey
$3.13M 37,691 -127,782 -77%
CA
125
Continental Advisors
Utah
$3.04M 36,700 +10,500 +40%
3 4
5
6 7