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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

611 hedge funds and large institutions have $9.72B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 268 reducing their positions, and 102 closing their positions.

Holders
611
Holders Change
-61
Holders Change %
-9.08%
% of All Funds
8.21%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
268
Closed
102
Calls
$1.14B
Puts
$1.97B
Net Calls
-$834M
Net Calls Change
+$252M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$1.5B
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.01B
3
Citigroup
3
Citigroup
New York
$1.06B
4
Wells Fargo
4
Wells Fargo
California
$243M
5
JFG
5
Jefferies Financial Group
New York
$119M

Top Sellers

1
DFG
1
Demars Financial Group
Washington
$247K
2
UBS Group
2
UBS Group
Switzerland
$341M
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$631M
4
HIIFS
4
Harel Insurance Investments & Financial Services
Israel
$0
5
Squarepoint
5
Squarepoint
New York
$39.2M
Name Market Value Shares Shares
Change 		Shares
Change %
MCM
51
Moore Capital Management
New York
$12.4M 150,000 +150,000 New
JF
52
Jump Financial
Illinois
$12.2M 147,626 -163,286 -53%
LRPA
53
L. Roy Papp & Associates
Arizona
$11.9M 143,241 -3,236 -2%
LI
54
LHM Inc
Utah
$11.9M 142,966 -856 -0.6%
Bank of Montreal
55
Bank of Montreal
Ontario, Canada
$11.7M 140,558 -14,867 -10%
Verition Fund Management
56
Verition Fund Management
Connecticut
$11.5M 138,297 +55,121 +66%
Thrivent Financial for Lutherans
57
Thrivent Financial for Lutherans
Minnesota
$11.3M 135,944 +58,499 +76%
Allspring Global Investments
58
Allspring Global Investments
North Carolina
$11.1M 134,066 -7,535 -5%
GS
59
GTS Securities
New York
$11M 132,820 +52,344 +65%
SG Americas Securities
60
SG Americas Securities
New York
$10.7M 128,763 -84 -0.1%
MFS
61
Madrona Financial Services
Washington
$10.4M 125,693 +125,693 New
Commonwealth Equity Services
62
Commonwealth Equity Services
Massachusetts
$10.2M 123,514 -13,845 -10%
WTC
63
WhitTier Trust Company
Nevada
$10.2M 122,518 -44,200 -27%
PEAK6
64
PEAK6
Illinois
$9.87M 118,991 -1,985 -2%
Northwestern Mutual Wealth Management
65
Northwestern Mutual Wealth Management
Wisconsin
$9.81M 118,278 -15,248 -11%
EWM
66
Edge Wealth Management
New York
$9.28M 111,927 +1,459 +1%
Osaic Holdings
67
Osaic Holdings
Arizona
$8.84M 99,372 -9,526 -9%
SCI
68
S&CO Inc
Massachusetts
$8.69M 104,837 +264 +0.3%
YLHM
69
Yelin Lapidot Holdings Management
Israel
$8.67M 104,532 – –
PI
70
Parkside Investments
Illinois
$8.62M 103,991 -16,566 -14%
Wealth Enhancement Advisory Services
71
Wealth Enhancement Advisory Services
Minnesota
$8.61M 100,986 -16,442 -14%
William Blair & Company
72
William Blair & Company
Illinois
$8.23M 99,220 -38,301 -28%
TBC
73
Ted Buchan & Co
California
$7.69M 92,754 +7,235 +8%
GJL
74
Gendell Jeffrey L
$7.65M 92,278 +53,432 +138%
IMPI
75
Ilmarinen Mutual Pension Insurance
Finland
$7.49M 90,329 – –
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3
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