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State Street SPDR S&P Biotech ETF

641 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 97 funds opening new positions, 148 increasing their positions, 238 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

more ownership

Funds ownership:

4% more funds holding

Funds holding: 618641 (+23)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 148 | Existing positions reduced: 238

Holders
641
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
BL
651
BCWM LLC
Kansas
LK
652
Lumbard & Kellner
New Hampshire
Renaissance Technologies
653
Renaissance Technologies
New York
QT
654
Quantbot Technologies
New York
BBVA
655
Banco Bilbao Vizcaya Argentaria
Spain
Citadel Advisors
656
Citadel Advisors
Florida
EFS
657
Econ Financial Services
Pennsylvania
Qube Research & Technologies (QRT)
658
Qube Research & Technologies (QRT)
United Kingdom
Capital Fund Management (CFM)
659
Capital Fund Management (CFM)
France
IMC Chicago
660
IMC Chicago
Illinois
BP
661
Ballentine Partners
Massachusetts
AC
662
ASB Consultores
Florida
PCM
663
Prelude Capital Management
New York
QOP
664
Quinn Opportunity Partners
Virginia
GCP
665
Garda Capital Partners
Minnesota
YC
666
Yarbrough Capital
Tennessee
AWC
667
Abundance Wealth Counselors
Pennsylvania
QGA
668
Q Global Advisors
Texas
LFAS
669
Level Four Advisory Services
Texas
HT
670
Headlands Technologies
Illinois
VPA
671
Vernal Point Advisors
California
JJBC
672
James J. Burns & Company
New York
SIG
673
Sargent Investment Group
Maryland
NEPWA
674
New England Private Wealth Advisors
Massachusetts
BAAM
675
Baker Avenue Asset Management
California