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State Street SPDR S&P Biotech ETF

641 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 97 funds opening new positions, 148 increasing their positions, 238 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

more ownership

Funds ownership:

4% more funds holding

Funds holding: 618641 (+23)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 148 | Existing positions reduced: 238

Holders
641
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
GC
426
Grimes & Company
Massachusetts
$279K
AWM
427
Aries Wealth Management
Maine
$277K
PCM
428
Parsons Capital Management
Rhode Island
$276K
SDAM
429
Shulman DeMeo Asset Management
New York
$276K
PCM
430
Poehling Capital Management
Wisconsin
$273K
MC
431
Moors & Cabot
Massachusetts
$272K
WA
432
Wealth Alliance
New York
$271K
BS
433
Banco Santander
Spain
$271K
DI
434
Diligent Investors
California
$271K
JIP
435
Jaffetilchin Investment Partners
Florida
$268K
LMKC
436
L.M. Kohn & Company
Ohio
$265K
PTC
437
Private Trust Company
Ohio
$264K
RWP
438
RWA Wealth Partners
Massachusetts
$261K
PWA
439
Prairie Wealth Advisors
Nebraska
$257K
IIC
440
Ironwood Investment Counsel
Arizona
$256K
M
441
MOTCO
Texas
$256K
Blackstone Inc
442
Blackstone Inc
New York
$255K
WC
443
Waterloo Capital
Texas
$255K
CIS
444
Continental Investors Services
Washington
$252K
HIA
445
Harbor Investment Advisory
Maryland
$252K
AWM
446
Apollon Wealth Management
South Carolina
$250K
AIM
447
Anchor Investment Management
South Carolina
$244K
RA
448
RFG Advisory
Alabama
$241K
SI
449
Stephens Inc
Arkansas
$240K
NWA
450
Navis Wealth Advisors
New York
$240K