XBI icon

State Street SPDR S&P Biotech ETF

641 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 97 funds opening new positions, 148 increasing their positions, 238 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

more ownership

Funds ownership:

4% more funds holding

Funds holding: 618641 (+23)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 148 | Existing positions reduced: 238

Holders
641
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
MC
401
Mathes Company
New York
$348K
CCG
402
Coastwise Capital Group
California
$346K
MIM
403
Miller Investment Management
Pennsylvania
$344K
SFA
404
Sequoia Financial Advisors
Ohio
$340K
UCFA
405
United Capital Financial Advisors
Texas
$334K
BFA
406
Beaumont Financial Advisors
Massachusetts
$331K
MG
407
Marex Group
$330K
IPAM
408
Investment Partners Asset Management
New Jersey
$326K
BFF
409
Byrne Financial Freedom
Massachusetts
$325K
SAM
410
Seelaus Asset Management
New Jersey
$324K
CB
411
Commerce Bank
Missouri
$318K
DA
412
Doliver Advisors
Texas
$316K
LWM
413
Lyell Wealth Management
California
$316K
BCWM
414
Bartlett & Co Wealth Management
Ohio
$313K
SAM
415
Sherman Asset Management
California
$309K
AWM
416
Accredited Wealth Management
Kentucky
$308K
AFS
417
AFG Fiduciary Services
Massachusetts
$305K
AWA
418
Amplius Wealth Advisors
Pennsylvania
$301K
PCM
419
Ping Capital Management
New York
$301K
FLC
420
Fifth Lane Capital
Texas
$301K
FFA
421
Fragasso Financial Advisors
Pennsylvania
$286K
EWS
422
Eagle Wealth Strategies
New Jersey
$284K
DFG
423
Demars Financial Group
Washington
$282K
OAC
424
OMERS Administration Corp
Ontario, Canada
$281K
DWT
425
Dorsey & Whitney Trust
South Dakota
$281K