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State Street SPDR S&P Biotech ETF

813 hedge funds and large institutions have $16.7B invested in State Street SPDR S&P Biotech ETF in 2026 Q1 according to their latest regulatory filings, with 107 funds opening new positions, 251 increasing their positions, 240 reducing their positions, and 94 closing their positions.

New
Increased
Maintained
Reduced
Closed

more ownership

Funds ownership:

more funds holding in top 10

Funds holding in top 10:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

1% more capital invested

Capital invested by funds: $16.5B → $16.7B (+$196M)

0% more funds holding

Funds holding: 812813 (+1)

54% less call options, than puts

Call options by funds: $2.19B | Put options by funds: $4.74B

Holders
813
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
22
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.19B
Puts
$4.74B
Net Calls
Net Calls Change

Top Buyers

1 +$570M
2 +$370M
3 +$212M
4
Barclays
Barclays
United Kingdom
+$118M
5
Morgan Stanley
Morgan Stanley
New York
+$105M

Top Sellers

1 -$771M
2 -$355M
3 -$256M
4
Citigroup
Citigroup
New York
-$233M
5
Two Sigma Investments
Two Sigma Investments
New York
-$177M
Name Holding Trade Value Shares
Change
Change in
Stake
IA
376
Integrity Alliance
Iowa
$774K
PNAA
377
Pictet North America Advisors
Switzerland
$769K
CMANY
378
Capital Management Associates (New York)
New York
$766K
SFP
379
Shepherd Financial Partners
Massachusetts
$763K
ONB
380
Old National Bancorp
Indiana
$762K
KA
381
Kercheville Advisors
Texas
$750K
TI
382
Tidal Investments
Wisconsin
$746K
EWA
383
EP Wealth Advisors
California
$736K
EAM
384
Empirical Asset Management
Massachusetts
$723K
CA
385
CWC Advisors
Oregon
$719K
AWF
386
Alpha Wealth Funds
Utah
$711K
AAP
387
Arax Advisory Partners
Colorado
$710K
PP
388
Patten & Patten
Tennessee
$699K
CPC
389
Congress Park Capital
New York
$693K
PFPG
390
Pinnacle Financial Partners (Georgia)
Georgia
$691K
BEC
391
Blue Edge Capital
Virginia
$687K
SWP
392
Stratos Wealth Partners
Ohio
$686K
WS
393
Wedbush Securities
California
$685K
AIP
394
Almanack Investment Partners
Pennsylvania
$678K
GT
395
Glenmede Trust
Pennsylvania
$673K
CA
396
Calton & Associates
Florida
$670K
Northern Trust
397
Northern Trust
Illinois
$665K
PFA
398
Pettinga Financial Advisors
Indiana
$659K
BHA
399
Beech Hill Advisors
New York
$659K
RG
400
Rathbones Group
United Kingdom
$654K