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State Street SPDR S&P Biotech ETF

641 hedge funds and large institutions have $12.4B invested in State Street SPDR S&P Biotech ETF in 2025 Q3 according to their latest regulatory filings, with 97 funds opening new positions, 148 increasing their positions, 238 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

more funds holding in top 10

Funds holding in top 10:

more ownership

Funds ownership:

4% more funds holding

Funds holding: 618641 (+23)

24% less call options, than puts

Call options by funds: $2.38B | Put options by funds: $3.15B

38% less repeat investments, than reductions

Existing positions increased: 148 | Existing positions reduced: 238

Holders
641
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
18
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$2.38B
Puts
$3.15B
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
FA
351
Fortis Advisors
Pennsylvania
$469K
NS
352
NBC Securities
Alabama
$468K
FNBT
353
FineMark National Bank & Trust
Florida
$466K
WS
354
Wedbush Securities
California
$463K
LNWWM
355
Laird Norton Wetherby Wealth Management
California
$462K
HL
356
HeadInvest LLC
Maine
$461K
CMMS
357
Comprehensive Money Management Services
Florida
$456K
EFS
358
Essex Financial Services
Connecticut
$451K
GIM
359
Glenmede Investment Management
Pennsylvania
$451K
AWM
360
Avaii Wealth Management
Wisconsin
$451K
RC
361
Roundview Capital
New Jersey
$449K
ABC
362
Associated Banc-Corp
Wisconsin
$448K
SF
363
Summit Financial
New Jersey
$447K
IC
364
IEQ Capital
California
$447K
MOS
365
MGO One Seven
Ohio
$447K
Zurich Cantonal Bank
366
Zurich Cantonal Bank
Switzerland
$446K
First Manhattan
367
First Manhattan
New York
$445K
CCG
368
Chatham Capital Group
Georgia
$442K
TRCT
369
Tower Research Capital (TRC)
New York
$442K
PCFFS
370
Pacific Center for Financial Services
California
$437K
BA
371
Bridgewater Advisors
New York
$433K
PCTC
372
Perkins Coie Trust Company
Washington
$429K
WAM
373
Worth Asset Management
Texas
$427K
PIA
374
Powell Investment Advisors
Florida
$425K
ATC
375
Advantage Trust Company
Kansas
$425K