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SPDR S&P Biotech ETF
XBI

Overview Fund Activity

613 hedge funds and large institutions have $9.73B invested in SPDR S&P Biotech ETF in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 159 increasing their positions, 270 reducing their positions, and 102 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
613
Holders Change
-59
Holders Change %
-8.78%
% of All Funds
8.22%
Holding in Top 10
15
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.2%
New
54
Increased
159
Reduced
270
Closed
102
Calls
$1.47B
Puts
$2.24B
Net Calls
-$777M
Net Calls Change
+$309M

Top Buyers

1
Goldman Sachs
Goldman Sachs
New York
$1.5B
2
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.01B
3
Citigroup
Citigroup
New York
$1.06B
4
Wells Fargo
Wells Fargo
California
$243M
5
JFG
Jefferies Financial Group
New York
$119M

Top Sellers

1
DFG
Demars Financial Group
Washington
$247K
2
UBS Group
UBS Group
Switzerland
$341M
3
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$631M
4
HIIFS
Harel Insurance Investments & Financial Services
Israel
$0
5
Squarepoint
Squarepoint
New York
$39.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
ARMT
476
Amica Retiree Medical Trust
Rhode Island
$117K – – –
SWA
477
SOA Wealth Advisors
New York
$116K -$12.5K -10,355 -10%
FFO
478
Fortitude Family Office
Arizona
$116K – – –
AF
479
Advisornet Financial
Minnesota
$113K -$1.16K -14 -1%
MTIC
480
Missouri Trust & Investment Company
Missouri
$110K – – –
HDIM
481
Hanson & Doremus Investment Management
Vermont
$108K -$29.5K -355 -21%
RAM
482
Ramirez Asset Management
New York
$106K -$16.6K -200 -14%
CLOS
483
Compagnie Lombard Odier SCmA
Switzerland
$103K – – –
DJSG
484
D.J. St. Germain
Massachusetts
$99.5K – – –
KFI
485
Key Financial Inc
Pennsylvania
$96.7K – – –
BRWA
486
B. Riley Wealth Advisors
Florida
$92.5K +$92.5K +1,115 New
WWM
487
Wolff Wiese Magana
California
$92.5K – – –
RFA
488
Register Financial Advisors
Georgia
$87.2K – – –
CA
489
CoreCap Advisors
Michigan
$86.8K – – –
MM
490
Main Management
California
$85K – – –
CPA
491
Cardiff Park Advisors
California
$82.9K +$82.9K +1,000 New
TCOV
492
Trust Company of Vermont
Vermont
$80.7K -$138K -1,660 -63%
HFS
493
Hopwood Financial Services
Virginia
$78.8K – – –
JHCP
494
Jackson Hole Capital Partners
Oklahoma
$78K -$74.6K -900 -49%
VCM
495
Versant Capital Management
Arizona
$74.6K -$74.6K -900 -50%
AWM
496
Activest Wealth Management
Florida
$72.5K +$62.8K +757 +647%
BCV
497
Banque Cantonale Vaudoise
Switzerland
$69K – – –
EWM
498
EPG Wealth Management
Georgia
$67.1K -$15.1K -182 -18%
FWP
499
FAS Wealth Partners
Kansas
$66.7K -$295K -3,555 -82%
PSFG
500
Park Square Financial Group
Georgia
$65.4K +$249 +3 +0.4%
18 19
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