UPB
Upstream Bio, Inc. Common Stock
82 hedge funds and large institutions have $531M invested in Upstream Bio, Inc. Common Stock in 2025 Q2 according to their latest regulatory filings, with 14 funds opening new positions, 41 increasing their positions, 13 reducing their positions, and 10 closing their positions.
New
Increased
Maintained
Reduced
Closed
Holders
82
Holders Change
+4
Holders Change %
+5.13%
% of All Funds
1.1%
Holding in Top 10
4
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
14
Increased
41
Reduced
13
Closed
10
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–
Top Buyers
| 1 |
Vanguard Group
Malvern,
Pennsylvania
|
+$13.9M |
| 2 |
BlackRock
New York
|
+$10M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
+$7.48M |
| 4 |
PHP
Parkman Healthcare Partners
Stamford,
Connecticut
|
+$5.29M |
| 5 |
Geode Capital Management
Boston,
Massachusetts
|
+$2.59M |
Top Sellers
| 1 |
AllianceBernstein
Nashville,
Tennessee
|
-$11.7M |
| 2 |
DTC
Deep Track Capital
Greenwich,
Connecticut
|
-$9.41M |
| 3 |
SB
Samsara BioCapital
Palo Alto,
California
|
-$6.85M |
| 4 |
Wellington Management Group
Boston,
Massachusetts
|
-$968K |
| 5 |
Millennium Management
New York
|
-$378K |
