US Bancorp
UPB

US Bancorp’s Upstream Bio Inc UPB Stock Holding History

US Bancorp’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$1.83K Sell
264
-326
-55% -$2.73K ﹤0.01% 3885
2026
Q1 		$5.31K Buy
590
+44
+8% +$792 ﹤0.01% 3549
2025
Q4 		$14.8K Buy
546
+15
+3% +$373 ﹤0.01% 3191
2025
Q3 		$9.99K Sell
531
-128
-19% -$1.99K ﹤0.01% 3313
2025
Q2 		$7.24K Buy
659
+97
+17% +$896 ﹤0.01% 3525
2025
Q1 		$3.44K Sell
562
-1,098
-66% -$10.5K ﹤0.01% 3757
2024
Q4 		$27.3K Buy
+1,660
New +$37.1K ﹤0.01% 3023

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

US Bancorp's UPB Position: Q2 2026 in Review

US Bancorp reduced its Upstream Bio Inc (UPB) stake by 55% in Q2 2026, selling an estimated $2.73K and leaving 264 shares worth $1.83K. The position accounts for ﹤0.01% of the portfolio, ranked #3885.

US Bancorp first reported a position in UPB in Q4 2024 and has held it in 7 quarters since. The position peaked at $27.3K in Q4 2024. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • US Bancorp held 264 shares of Upstream Bio Inc worth $1.83K as of Q2 2026.
  • US Bancorp sold 326 Upstream Bio Inc shares in Q2 2026, an estimated $2.73K.
  • Upstream Bio Inc made up ﹤0.01% of US Bancorp's portfolio in Q2 2026, its #3885 holding.
  • US Bancorp first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 7 quarters since.
  • US Bancorp's Upstream Bio Inc position peaked at $27.3K in Q4 2024.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on US Bancorp's 13F filing for Q2 2026, filed 12 Aug 2026.