SO
UPB

STRS Ohio’s Upstream Bio Inc UPB Stock Holding History

STRS Ohio’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$88.2K Hold
9,800
– – ﹤0.01% 1814
2025
Q4 		$266K Buy
+9,800
New +$244K ﹤0.01% 1388
2025
Q3 		– Sell
-1,800
Closed -$19.8K – 2303
2025
Q2 		$19.8K Sell
1,800
-1,400
-44% -$12.9K ﹤0.01% 2135
2025
Q1 		$19.6K Hold
3,200
– – ﹤0.01% 1850
2024
Q4 		$52.6K Buy
+3,200
New +$71.5K ﹤0.01% 1726

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

STRS Ohio's UPB Position: Q1 2026 in Review

STRS Ohio held its Upstream Bio Inc (UPB) position steady in Q1 2026 at 9,800 shares worth $88.2K. The position accounts for ﹤0.01% of the portfolio, ranked #1814.

STRS Ohio first reported a position in UPB in Q4 2024 and has held it in 5 quarters since. The position peaked at $266K in Q4 2025. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • STRS Ohio held 9,800 shares of Upstream Bio Inc worth $88.2K as of Q1 2026.
  • STRS Ohio left its Upstream Bio Inc share count unchanged in Q1 2026.
  • Upstream Bio Inc made up ﹤0.01% of STRS Ohio's portfolio in Q1 2026, its #1814 holding.
  • STRS Ohio first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 5 quarters since.
  • STRS Ohio's Upstream Bio Inc position peaked at $266K in Q4 2025.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on STRS Ohio's 13F filing for Q1 2026, filed 24 Apr 2026.