SO
UPB

STRS Ohio’s Upstream Bio Inc UPB Stock Holding History

STRS Ohio’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$83K Buy
12,000
+2,200
+22% +$18.4K ﹤0.01% 1913
2026
Q1 		$88.2K Hold
9,800
– – ﹤0.01% 1814
2025
Q4 		$266K Buy
+9,800
New +$244K ﹤0.01% 1388
2025
Q3 		– Sell
-1,800
Closed -$19.8K – 2303
2025
Q2 		$19.8K Sell
1,800
-1,400
-44% -$12.9K ﹤0.01% 2135
2025
Q1 		$19.6K Hold
3,200
– – ﹤0.01% 1850
2024
Q4 		$52.6K Buy
+3,200
New +$71.5K ﹤0.01% 1726

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

STRS Ohio's UPB Position: Q2 2026 in Review

STRS Ohio increased its Upstream Bio Inc (UPB) stake by 22% in Q2 2026, buying an estimated $18.4K and bringing the position to 12,000 shares worth $83K. The position accounts for ﹤0.01% of the portfolio, ranked #1913.

STRS Ohio first reported a position in UPB in Q4 2024 and has held it in 6 quarters since. The position peaked at $266K in Q4 2025. 149 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • STRS Ohio held 12,000 shares of Upstream Bio Inc worth $83K as of Q2 2026.
  • STRS Ohio bought 2,200 Upstream Bio Inc shares in Q2 2026, an estimated $18.4K.
  • Upstream Bio Inc made up ﹤0.01% of STRS Ohio's portfolio in Q2 2026, its #1913 holding.
  • STRS Ohio first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 6 quarters since.
  • STRS Ohio's Upstream Bio Inc position peaked at $266K in Q4 2025.
  • 149 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on STRS Ohio's 13F filing for Q2 2026, filed 30 Jul 2026.