QCM
UPB

Quantinno Capital Management’s Upstream Bio Inc UPB Stock Holding History

Quantinno Capital Management’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$445K Buy
49,389
+33,974
+220% +$611K ﹤0.01% 2798
2025
Q4 		$419K Buy
15,415
+526
+4% +$13.1K ﹤0.01% 2592
2025
Q3 		$280K Buy
14,889
+4,275
+40% +$66.4K ﹤0.01% 2511
2025
Q2 		$117K Sell
10,614
-4,611
-30% -$42.6K ﹤0.01% 2480
2025
Q1 		$93.2K Buy
+15,225
New +$145K ﹤0.01% 2040

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Quantinno Capital Management's UPB Position: Q1 2026 in Review

Quantinno Capital Management increased its Upstream Bio Inc (UPB) stake by 220% in Q1 2026, buying an estimated $611K and bringing the position to 49,389 shares worth $445K. The position accounts for ﹤0.01% of the portfolio, ranked #2798.

Quantinno Capital Management first reported a position in UPB in Q1 2025 and has held it in 5 quarters since. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • Quantinno Capital Management held 49,389 shares of Upstream Bio Inc worth $445K as of Q1 2026.
  • Quantinno Capital Management bought 33,974 Upstream Bio Inc shares in Q1 2026, an estimated $611K.
  • Upstream Bio Inc made up ﹤0.01% of Quantinno Capital Management's portfolio in Q1 2026, its #2798 holding.
  • Quantinno Capital Management first reported a position in Upstream Bio Inc in Q1 2025 and has held it in 5 quarters since.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on Quantinno Capital Management's 13F filing for Q1 2026, filed 15 May 2026.