QCM
UPB

Quantinno Capital Management’s Upstream Bio Inc UPB Stock Holding History

Quantinno Capital Management’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$379K Buy
54,838
+5,449
+11% +$45.7K ﹤0.01% 3114
2026
Q1 		$445K Buy
49,389
+33,974
+220% +$611K ﹤0.01% 2798
2025
Q4 		$419K Buy
15,415
+526
+4% +$13.1K ﹤0.01% 2592
2025
Q3 		$280K Buy
14,889
+4,275
+40% +$66.4K ﹤0.01% 2511
2025
Q2 		$117K Sell
10,614
-4,611
-30% -$42.6K ﹤0.01% 2480
2025
Q1 		$93.2K Buy
+15,225
New +$145K ﹤0.01% 2040

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Quantinno Capital Management's UPB Position: Q2 2026 in Review

Quantinno Capital Management increased its Upstream Bio Inc (UPB) stake by 11% in Q2 2026, buying an estimated $45.7K and bringing the position to 54,838 shares worth $379K. The position accounts for ﹤0.01% of the portfolio, ranked #3114.

Quantinno Capital Management first reported a position in UPB in Q1 2025 and has held it in 6 quarters since. The position peaked at $445K in Q1 2026. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Quantinno Capital Management held 54,838 shares of Upstream Bio Inc worth $379K as of Q2 2026.
  • Quantinno Capital Management bought 5,449 Upstream Bio Inc shares in Q2 2026, an estimated $45.7K.
  • Upstream Bio Inc made up ﹤0.01% of Quantinno Capital Management's portfolio in Q2 2026, its #3114 holding.
  • Quantinno Capital Management first reported a position in Upstream Bio Inc in Q1 2025 and has held it in 6 quarters since.
  • Quantinno Capital Management's Upstream Bio Inc position peaked at $445K in Q1 2026.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Quantinno Capital Management's 13F filing for Q2 2026, filed 13 Aug 2026.