Vanguard Group’s Upstream Bio, Inc. Common Stock UPB Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Shares Change %	Capital Flow	Portfolio Weight	Portfolio Position
2025 Q2	$23.8M	Buy	2,170,833 +1,263,807	+139%	+$13.9M	﹤0.01%	2477
2025 Q1	$5.55M	Sell	907,026 -7,995	-0.9%	-$48.9K	﹤0.01%	3128
2024 Q4	$15M	Buy	+915,021	New	+$15M	﹤0.01%	2738