TRCT
UPB

Tower Research Capital (TRC)’s Upstream Bio Inc UPB Stock Holding History

Tower Research Capital (TRC)’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$33.1K Buy
4,788
+3,363
+236% +$28.2K ﹤0.01% 3088
2026
Q1 		$12.8K Buy
1,425
+756
+113% +$13.6K ﹤0.01% 3771
2025
Q4 		$18.2K Sell
669
-1,199
-64% -$29.8K ﹤0.01% 3173
2025
Q3 		$35.1K Sell
1,868
-1,183
-39% -$18.4K ﹤0.01% 2803
2025
Q2 		$33.5K Buy
3,051
+1,469
+93% +$13.6K ﹤0.01% 3318
2025
Q1 		$9.68K Sell
1,582
-1,264
-44% -$12.1K ﹤0.01% 3745
2024
Q4 		$46.8K Buy
+2,846
New +$63.5K ﹤0.01% 2600

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Tower Research Capital (TRC)'s UPB Position: Q2 2026 in Review

Tower Research Capital (TRC) increased its Upstream Bio Inc (UPB) stake by 236% in Q2 2026, buying an estimated $28.2K and bringing the position to 4,788 shares worth $33.1K. The position accounts for ﹤0.01% of the portfolio, ranked #3088.

Tower Research Capital (TRC) first reported a position in UPB in Q4 2024 and has held it in 7 quarters since. The position peaked at $46.8K in Q4 2024. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Tower Research Capital (TRC) held 4,788 shares of Upstream Bio Inc worth $33.1K as of Q2 2026.
  • Tower Research Capital (TRC) bought 3,363 Upstream Bio Inc shares in Q2 2026, an estimated $28.2K.
  • Upstream Bio Inc made up ﹤0.01% of Tower Research Capital (TRC)'s portfolio in Q2 2026, its #3088 holding.
  • Tower Research Capital (TRC) first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 7 quarters since.
  • Tower Research Capital (TRC)'s Upstream Bio Inc position peaked at $46.8K in Q4 2024.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Tower Research Capital (TRC)'s 13F filing for Q2 2026, filed 11 Aug 2026.