TRCT
UPB

Tower Research Capital (TRC)’s Upstream Bio Inc UPB Stock Holding History

Tower Research Capital (TRC)’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$12.8K Buy
1,425
+756
+113% +$13.6K ﹤0.01% 3771
2025
Q4 		$18.2K Sell
669
-1,199
-64% -$29.8K ﹤0.01% 3173
2025
Q3 		$35.1K Sell
1,868
-1,183
-39% -$18.4K ﹤0.01% 2803
2025
Q2 		$33.5K Buy
3,051
+1,469
+93% +$13.6K ﹤0.01% 3318
2025
Q1 		$9.68K Sell
1,582
-1,264
-44% -$12.1K ﹤0.01% 3745
2024
Q4 		$46.8K Buy
+2,846
New +$63.5K ﹤0.01% 2600

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Tower Research Capital (TRC)'s UPB Position: Q1 2026 in Review

Tower Research Capital (TRC) increased its Upstream Bio Inc (UPB) stake by 113% in Q1 2026, buying an estimated $13.6K and bringing the position to 1,425 shares worth $12.8K. The position accounts for ﹤0.01% of the portfolio, ranked #3771.

Tower Research Capital (TRC) first reported a position in UPB in Q4 2024 and has held it in 6 quarters since. The position peaked at $46.8K in Q4 2024. 140 funds tracked by Wall St. Rank hold UPB as of Q1 2026.

  • Tower Research Capital (TRC) held 1,425 shares of Upstream Bio Inc worth $12.8K as of Q1 2026.
  • Tower Research Capital (TRC) bought 756 Upstream Bio Inc shares in Q1 2026, an estimated $13.6K.
  • Upstream Bio Inc made up ﹤0.01% of Tower Research Capital (TRC)'s portfolio in Q1 2026, its #3771 holding.
  • Tower Research Capital (TRC) first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 6 quarters since.
  • Tower Research Capital (TRC)'s Upstream Bio Inc position peaked at $46.8K in Q4 2024.
  • 140 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q1 2026.

Based on Tower Research Capital (TRC)'s 13F filing for Q1 2026, filed 15 May 2026.