UPB

Upstream Bio, Inc. Common Stock

81 hedge funds and large institutions have $530M invested in Upstream Bio, Inc. Common Stock in 2025 Q2 according to their latest regulatory filings, with 14 funds opening new positions, 40 increasing their positions, 13 reducing their positions, and 10 closing their positions.

Holders
81
Holders Change
+3
Holders Change %
+3.85%
% of All Funds
1.09%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
14
Increased
40
Reduced
13
Closed
10
Calls
Puts
Net Calls
Net Calls Change
Name Market Value Shares Shares
Change
Shares
Change %
Commonwealth Equity Services
51
Commonwealth Equity Services
Massachusetts
$170K 15,526 +15,526 New
Creative Planning
52
Creative Planning
Kansas
$154K 14,030 +14,030 New
Manulife (Manufacturers Life Insurance)
53
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$145K 13,190 +13,190 New
Citigroup
54
Citigroup
New York
$128K 11,695 -6,483 -36%
QCM
55
Quantinno Capital Management
New York
$117K 10,614 -4,611 -30%
VIA
56
Virtus Investment Advisers
Connecticut
$89.3K 8,134 +8,134 New
PFSRSONJ
57
Police & Firemen's Retirement System of New Jersey
New Jersey
$86K 7,833 +4,483 +134%
New York State Common Retirement Fund
58
New York State Common Retirement Fund
New York
$52K 4,700
AIP
59
Ameritas Investment Partners
Nebraska
$39.1K 3,558 +1,736 +95%
Carson Wealth (CWM LLC)
60
Carson Wealth (CWM LLC)
Nebraska
$36K 3,312 +1,716 +108%
Legal & General Group
61
Legal & General Group
United Kingdom
$34.9K 3,174 +1,440 +83%
BNP Paribas Financial Markets
62
BNP Paribas Financial Markets
France
$34K 3,097 +2,158 +230%
TRCT
63
Tower Research Capital (TRC)
New York
$33.5K 3,051 +1,469 +93%
Royal Bank of Canada
64
Royal Bank of Canada
Ontario, Canada
$33K 3,090 +2,258 +271%
California State Teachers Retirement System (CalSTRS)
65
California State Teachers Retirement System (CalSTRS)
California
$23.9K 2,174 +884 +69%
SO
66
STRS Ohio
Ohio
$19.8K 1,800 -1,400 -44%
SCM
67
Sterling Capital Management
North Carolina
$10.3K 941 +804 +587%
GI
68
GAMMA Investing
California
$7.61K 693 +100 +17%
US Bancorp
69
US Bancorp
Minnesota
$7.24K 659 +97 +17%
AB
70
Amalgamated Bank
New York
$7K 594
VCM
71
Versant Capital Management
Arizona
$6.13K 558 -57 -9%
EWA
72
EverSource Wealth Advisors
Alabama
$3.39K 309 +174 +129%
CIAM
73
Caitong International Asset Management
Hong Kong
$2.46K 224 +224 New
CA
74
Clearstead Advisors
Ohio
$1.79K 163 +163 New
Russell Investments Group
75
Russell Investments Group
United Kingdom
$1.61K 147 +147 New