Federated Hermes’s Upstream Bio Inc UPB Stock Holding History

Federated Hermes’s Portfolio UPB Stock Details UPB Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	–	Sell	-979,758	Closed	-$8.82M	–	2211
2026 Q1	$8.82M	Buy	979,758 +979,276	+203,169%	+$17.6M	0.01%	676
2025 Q4	$13.1K	Buy	+482	New	+$12K	﹤0.01%	1814

Other funds holding UPB

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return

Norges Bank Oslo, Norway $1T AUM

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return

Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Millennium Management New York $276B AUM 44.8% 1-Year Est. Return

D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return

JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Federated Hermes's UPB Position: Q2 2026 in Review

Federated Hermes sold out of Upstream Bio Inc (UPB) in Q2 2026, closing a stake of 979,758 shares — an estimated $8.82M sold.

Federated Hermes first reported a position in UPB in Q4 2025 and held it in 2 quarters. The position peaked at $8.82M in Q1 2026. 149 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

Federated Hermes reported no remaining Upstream Bio Inc position as of Q2 2026 after selling out during the quarter.
Federated Hermes sold 979,758 Upstream Bio Inc shares in Q2 2026, an estimated $8.82M.
Federated Hermes first reported a position in Upstream Bio Inc in Q4 2025 and held it in 2 quarters.
Federated Hermes's Upstream Bio Inc position peaked at $8.82M in Q1 2026.
149 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Federated Hermes's 13F filing for Q2 2026, filed 12 Aug 2026.