UPB
Upstream Bio Inc
UPB
UPB
140 hedge funds and large institutions have $404M invested in Upstream Bio Inc in 2026 Q1 according to their latest regulatory filings, with 47 funds opening new positions, 47 increasing their positions, 35 reducing their positions, and 37 closing their positions.
New
Increased
Maintained
Reduced
Closed
more repeat investments, than reductions
Existing positions increased: | Existing positions reduced:
more first-time investments, than exits
New positions opened: | Existing positions closed:
more call options, than puts
Call options by funds: $ | Put options by funds: $
more funds holding
Funds holding: →
12.22% less ownership
Funds ownership: 94.7% → 82.48% (-12%)
67% less funds holding in top 10
Funds holding in top 10: 6 → 2 (-4)
71% less capital invested
Capital invested by funds: $1.39B → $404M (-$985M)
Holders
140
Holding in Top 10
2
Calls
$972K
Puts
$872K
Top Buyers
| 1 | +$17.6M | |
| 2 | +$17.2M | |
| 3 | +$14.3M | |
| 4 |
HSBC Holdings
London,
United Kingdom
|
+$11.5M |
| 5 |
Qube Research & Technologies (QRT)
London,
United Kingdom
|
+$11.1M |
Top Sellers
| 1 | -$41.4M | |
| 2 | -$36M | |
| 3 | -$31.7M | |
| 4 |
UBS Group
Zurich,
Switzerland
|
-$28.3M |
| 5 |
IHAM
Integral Health Asset Management
New York
|
-$20.4M |
