T. Rowe Price Associates
UPB

T. Rowe Price Associates’s Upstream Bio Inc UPB Stock Holding History

T. Rowe Price Associates’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$195K Buy
28,058
+1,624
+6% +$13.6K ﹤0.01% 3015
2026
Q1 		$238K Buy
26,434
+6,798
+35% +$122K ﹤0.01% 2773
2025
Q4 		$534K Buy
19,636
+1,135
+6% +$28.3K ﹤0.01% 2368
2025
Q3 		$349K Buy
18,501
+1,053
+6% +$16.4K ﹤0.01% 2529
2025
Q2 		$192K Buy
+17,448
New +$161K ﹤0.01% 2729

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

T. Rowe Price Associates's UPB Position: Q2 2026 in Review

T. Rowe Price Associates increased its Upstream Bio Inc (UPB) stake by 6.1% in Q2 2026, buying an estimated $13.6K and bringing the position to 28,058 shares worth $195K. The position accounts for ﹤0.01% of the portfolio, ranked #3015.

T. Rowe Price Associates first reported a position in UPB in Q2 2025 and has held it in 5 quarters since. The position peaked at $534K in Q4 2025. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • T. Rowe Price Associates held 28,058 shares of Upstream Bio Inc worth $195K as of Q2 2026.
  • T. Rowe Price Associates bought 1,624 Upstream Bio Inc shares in Q2 2026, an estimated $13.6K.
  • Upstream Bio Inc made up ﹤0.01% of T. Rowe Price Associates's portfolio in Q2 2026, its #3015 holding.
  • T. Rowe Price Associates first reported a position in Upstream Bio Inc in Q2 2025 and has held it in 5 quarters since.
  • T. Rowe Price Associates's Upstream Bio Inc position peaked at $534K in Q4 2025.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on T. Rowe Price Associates's 13F filing for Q2 2026, filed 14 Aug 2026.