|
1
|
|
$489M
|
–
|
–
|
–
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$328M
|
–
|
–
|
–
|
|
|
3
|
Paradigm Biocapital Advisors
New York
|
$232M
|
+$23.8M
|
+823,828
|
+13%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$207M
|
–
|
–
|
–
|
|
|
5
|
|
$204M
|
-$4.54M
|
-157,585
|
-2%
|
|
|
6
|
Janus Henderson Group
London,
|
$186M
|
+$38.9M
|
+1,348,706
|
+30%
|
|
|
7
|
Novo Holdings A/S
Hellerup,
Denmark
|
$169M
|
–
|
–
|
–
|
|
|
8
|
Driehaus Capital Management
Chicago,
Illinois
|
$141M
|
+$8.27M
|
+286,749
|
+7%
|
|
|
9
|
Siren LLC
Greenwich,
Connecticut
|
$140M
|
-$2.88M
|
-99,727
|
-2%
|
|
|
10
|
Perceptive Advisors
New York
|
$139M
|
-$980K
|
-34,000
|
-0.8%
|
|
|
11
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$119M
|
+$109M
|
+3,788,161
|
New
|
|
|
12
|
Cormorant Asset Management
Boston,
Massachusetts
|
$103M
|
-$721K
|
-25,000
|
-0.8%
|
|
|
13
|
Braidwell
Stamford,
Connecticut
|
$73.9M
|
-$82.6M
|
-2,863,248
|
-55%
|
|
|
14
|
|
$70.7M
|
-$19.2M
|
-664,853
|
-23%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$56.4M
|
+$1.26M
|
+43,597
|
+2%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$54.1M
|
-$15K
|
-520
|
-0%
|
|
|
17
|
MPM BioImpact
Boston,
Massachusetts
|
$52.3M
|
+$157K
|
+5,440
|
+0.3%
|
|
|
18
|
Integral Health Asset Management
New York
|
$50.4M
|
+$2.88M
|
+100,000
|
+7%
|
|
|
19
|
Bellevue Group
Kuesnacht,
Switzerland
|
$48.1M
|
–
|
–
|
–
|
|
|
20
|
Soleus Capital Management
Greenwich,
Connecticut
|
$45.7M
|
+$15.6M
|
+539,915
|
+59%
|
|
|
21
|
AllianceBernstein
Nashville,
Tennessee
|
$42.7M
|
+$19.8M
|
+685,999
|
+66%
|
|
|
22
|
Bank of America
Charlotte,
North Carolina
|
$41.8M
|
-$4.25M
|
-147,437
|
-10%
|
|
|
23
|
UBS Group
Zurich,
Switzerland
|
$41.3M
|
-$23.2M
|
-805,948
|
-38%
|
|
|
24
|
Dimensional Fund Advisors
Austin,
Texas
|
$38.4M
|
+$175K
|
+6,060
|
+0.5%
|
|
|
25
|
American Century Companies
Kansas City,
Missouri
|
$36.1M
|
-$1.13M
|
-39,291
|
-3%
|
|
