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Edgewise Therapeutics
EWTX

Overview Fund Activity

176 hedge funds and large institutions have $1.55B invested in Edgewise Therapeutics in 2025 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 87 increasing their positions, 38 reducing their positions, and 41 closing their positions.

Holders
176
Holders Change
-15
Holders Change %
-7.85%
% of All Funds
2.36%
Holding in Top 10
8
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-20%
% of All Funds
0.11%
New
31
Increased
87
Reduced
38
Closed
41
Calls
$571K
Puts
$751K
Net Calls
-$180K
Net Calls Change
-$29.1M

Top Buyers

1
B
1
Braidwell
Connecticut
$68.3M
2
PBA
2
Paradigm Biocapital Advisors
New York
$80.5M
3
SL
3
Siren LLC
Connecticut
$41.4M
4
BG
4
Bellevue Group
Switzerland
$36.4M
5
BBA
5
Baker Bros. Advisors
New York
$95.8M

Top Sellers

1
DTC
1
Deep Track Capital
Connecticut
$0
2
PA
2
Perceptive Advisors
New York
$60.8M
3
Viking Global Investors
3
Viking Global Investors
Connecticut
$0
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$0
5
RAM
5
Readystate Asset Management
Illinois
$0
Name Market Value Shares Shares
Change 		Shares
Change %
O
1
OrbiMed
New York
$203M 15,518,492 +496,771 +3%
RCM
2
RA Capital Management
Massachusetts
$130M 9,902,633 +993,542 +11%
BBA
3
Baker Bros. Advisors
New York
$95.8M 7,305,940 +1,150,000 +19%
BlackRock
4
BlackRock
New York
$88.9M 6,781,046 +296,038 +5%
PBA
5
Paradigm Biocapital Advisors
New York
$80.5M 6,142,344 +1,747,788 +40%
Janus Henderson Group
6
Janus Henderson Group
United Kingdom
$72.1M 5,503,349 +221,195 +4%
NHAS
7
Novo Holdings A/S
Denmark
$70.1M 5,350,000 – –
B
8
Braidwell
Connecticut
$68.3M 5,210,831 +2,752,023 +112%
Vanguard Group
9
Vanguard Group
Pennsylvania
$63.5M 4,841,500 +547,096 +13%
PA
10
Perceptive Advisors
New York
$60.8M 4,639,949 -1,907,379 -29%
CAM
11
Cormorant Asset Management
Massachusetts
$55.7M 4,251,992 +150,000 +4%
SL
12
Siren LLC
Connecticut
$41.4M 3,160,298 +1,463,854 +86%
BG
13
Bellevue Group
Switzerland
$36.4M 2,775,997 +1,347,068 +94%
DCM
14
Driehaus Capital Management
Illinois
$27.6M 2,101,781 +726,039 +53%
DM
15
Deerfield Management
New York
$27.1M 2,067,320 -11,189 -0.5%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$23.6M 1,797,215 +141,551 +9%
State Street
17
State Street
Massachusetts
$23.4M 1,781,501 +63,777 +4%
MB
18
MPM BioImpact
Massachusetts
$22.6M 1,720,741 +615,297 +56%
FLAM
19
First Light Asset Management
Minnesota
$22.5M 1,714,019 -138,271 -7%
Artisan Partners
20
Artisan Partners
Wisconsin
$18.1M 1,379,068 +461,846 +50%
WP
21
Woodline Partners
California
$14.4M 1,096,863 +54 +0%
Dimensional Fund Advisors
22
Dimensional Fund Advisors
Texas
$13.8M 1,048,936 +381,437 +57%
NLVP
23
New Leaf Venture Partners
New York
$13.5M 1,030,161 – –
IHAM
24
Integral Health Asset Management
New York
$13.1M 1,000,000 +325,000 +48%
PCH
25
Polar Capital Holdings
United Kingdom
$12.8M 975,000 +725,000 +290%
1
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