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Edgewise Therapeutics

214 hedge funds and large institutions have $3.72B invested in Edgewise Therapeutics in 2026 Q1 according to their latest regulatory filings, with 44 funds opening new positions, 65 increasing their positions, 66 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

83% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 24

69% more call options, than puts

Call options by funds: $18.7M | Put options by funds: $11.1M

23% more capital invested

Capital invested by funds: $3.02B → $3.72B (+$699M)

10% more funds holding in top 10

Funds holding in top 10: 1011 (+1)

8% more funds holding

Funds holding: 199214 (+15)

2% less repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 66

4.57% less ownership

Funds ownership: 115.07%110.5% (-4.6%)

Holders
214
Holders Change
+15
Holders Change %
+7.54%
% of All Funds
2.63%
Holding in Top 10
11
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+10%
% of All Funds
0.14%
New
44
Increased
65
Reduced
66
Closed
24
Calls
$18.7M
Puts
$11.1M
Net Calls
+$7.66M
Net Calls Change
+$6.35M
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$489M
RCM
2
RA Capital Management
Massachusetts
$328M
PBA
3
Paradigm Biocapital Advisors
New York
$232M +$23.8M +823,828 +13%
BBA
4
Baker Bros. Advisors
New York
$207M
BlackRock
5
BlackRock
New York
$204M -$4.54M -157,585 -2%
Janus Henderson Group
6
Janus Henderson Group
United Kingdom
$186M +$38.9M +1,348,706 +30%
NHAS
7
Novo Holdings A/S
Denmark
$169M
DCM
8
Driehaus Capital Management
Illinois
$141M +$8.27M +286,749 +7%
SL
9
Siren LLC
Connecticut
$140M -$2.88M -99,727 -2%
PA
10
Perceptive Advisors
New York
$139M -$980K -34,000 -0.8%
VCM
11
Vanguard Capital Management
Pennsylvania
$119M +$109M +3,788,161 New
CAM
12
Cormorant Asset Management
Massachusetts
$103M -$721K -25,000 -0.8%
B
13
Braidwell
Connecticut
$73.9M -$82.6M -2,863,248 -55%
Morgan Stanley
14
Morgan Stanley
New York
$70.7M -$19.2M -664,853 -23%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$56.4M +$1.26M +43,597 +2%
State Street
16
State Street
Massachusetts
$54.1M -$15K -520 -0%
MB
17
MPM BioImpact
Massachusetts
$52.3M +$157K +5,440 +0.3%
IHAM
18
Integral Health Asset Management
New York
$50.4M +$2.88M +100,000 +7%
BG
19
Bellevue Group
Switzerland
$48.1M
SCM
20
Soleus Capital Management
Connecticut
$45.7M +$15.6M +539,915 +59%
AllianceBernstein
21
AllianceBernstein
Tennessee
$42.7M +$19.8M +685,999 +66%
Bank of America
22
Bank of America
North Carolina
$41.8M -$4.25M -147,437 -10%
UBS Group
23
UBS Group
Switzerland
$41.3M -$23.2M -805,948 -38%
Dimensional Fund Advisors
24
Dimensional Fund Advisors
Texas
$38.4M +$175K +6,060 +0.5%
American Century Companies
25
American Century Companies
Missouri
$36.1M -$1.13M -39,291 -3%