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Edgewise Therapeutics
EWTX

Overview Fund Activity

191 hedge funds and large institutions have $2.32B invested in Edgewise Therapeutics in 2025 Q1 according to their latest regulatory filings, with 33 funds opening new positions, 68 increasing their positions, 62 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
191
Holders Change
-9
Holders Change %
-4.5%
% of All Funds
2.59%
Holding in Top 10
10
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+11.11%
% of All Funds
0.14%
New
33
Increased
68
Reduced
62
Closed
39
Calls
$61.6M
Puts
$32.7M
Net Calls
+$28.9M
Net Calls Change
+$15.4M

Top Buyers

1
PA
Perceptive Advisors
New York
+$85M
2
FLAM
First Light Asset Management
Minnesota
+$23.6M
3
SL
Siren LLC
Connecticut
+$21.2M
4
CAM
Cormorant Asset Management
Massachusetts
+$15.3M
5
DTC
Deep Track Capital
Connecticut
+$15.2M

Top Sellers

1
FLSM
Frazier Life Sciences Management
California
-$33.9M
2
Viking Global Investors
Viking Global Investors
Connecticut
-$16.2M
3
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$12M
4
LGM
Logos Global Management
California
-$10.7M
5
Citadel Advisors
Citadel Advisors
Florida
-$8.19M
Name Holding Trade Value Shares
Change 		Shares
Change %
O
1
OrbiMed
New York
$330M – – –
RCM
2
RA Capital Management
Massachusetts
$196M – – –
PA
3
Perceptive Advisors
New York
$144M +$85M +3,861,791 +144%
BlackRock
4
BlackRock
New York
$143M +$132K +5,993 +0.1%
BBA
5
Baker Bros. Advisors
New York
$135M – – –
Janus Henderson Group
6
Janus Henderson Group
United Kingdom
$123M +$6.94M +298,214 +6%
NHAS
7
Novo Holdings A/S
Denmark
$118M +$7.7M +350,000 +7%
PBA
8
Paradigm Biocapital Advisors
New York
$96.7M -$2.19M -99,373 -2%
Vanguard Group
9
Vanguard Group
Pennsylvania
$94.5M -$3.79M -172,445 -4%
CAM
10
Cormorant Asset Management
Massachusetts
$90.2M +$15.3M +695,458 +20%
B
11
Braidwell
Connecticut
$54.1M +$2.79M +126,612 +5%
DM
12
Deerfield Management
New York
$45.7M – – –
FLAM
13
First Light Asset Management
Minnesota
$40.8M +$23.6M +1,071,651 +137%
State Street
14
State Street
Massachusetts
$37.8M +$47.9K +2,179 +0.1%
SL
15
Siren LLC
Connecticut
$37.3M +$21.2M +962,101 +131%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$36.4M +$1.21M +55,093 +3%
BG
17
Bellevue Group
Switzerland
$31.4M – – –
DTC
18
Deep Track Capital
Connecticut
$30.8M +$15.2M +689,579 +97%
DCM
19
Driehaus Capital Management
Illinois
$30.3M -$2.6M -118,049 -8%
MB
20
MPM BioImpact
Massachusetts
$24.3M +$575K +26,128 +2%
WP
21
Woodline Partners
California
$24.1M +$11.7M +529,591 +93%
NLVP
22
New Leaf Venture Partners
New York
$22.7M – – –
Artisan Partners
23
Artisan Partners
Wisconsin
$20.2M -$3.4M -154,374 -14%
American Century Companies
24
American Century Companies
Missouri
$17.2M +$207K +9,413 +1%
Bank of America
25
Bank of America
North Carolina
$15.3M +$14.2M +646,519 +1,322%
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