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Siren LLC’s Edgewise Therapeutics EWTX Stock Holding History

Siren LLC’s Portfolio EWTX Stock Details EWTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$140M Sell
4,430,263
-99,727
-2% -$2.88M 3.87% 4
2025
Q4 		$112M Buy
4,529,990
+632,891
+16% +$12.7M 3.35% 4
2025
Q3 		$63.2M Buy
3,897,099
+736,801
+23% +$10.5M 2.47% 8
2025
Q2 		$41.4M Buy
3,160,298
+1,463,854
+86% +$21.1M 2.14% 13
2025
Q1 		$37.3M Buy
1,696,444
+962,101
+131% +$25.2M 2.11% 14
2024
Q4 		$19.6M Buy
734,343
+330,230
+82% +$10.5M 0.87% 32
2024
Q3 		$10.8M Buy
+404,113
New +$8.04M 0.54% 41

Other funds holding EWTX

O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
PBA
Paradigm Biocapital Advisors New York $4.89B AUM 251.12% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
NHAS
Novo Holdings A/S Hellerup, Denmark $1.23B AUM 81.32% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Siren LLC's EWTX Position: Q1 2026 in Review

Siren LLC reduced its Edgewise Therapeutics (EWTX) stake by 2.2% in Q1 2026, selling an estimated $2.88M and leaving 4,430,263 shares worth $140M. The position accounts for 3.87% of the portfolio, ranked #4.

Siren LLC first reported a position in EWTX in Q3 2024 and has held it in 7 quarters since. 214 funds tracked by Wall St. Rank hold EWTX as of Q1 2026.

  • Siren LLC held 4,430,263 shares of Edgewise Therapeutics worth $140M as of Q1 2026.
  • Siren LLC sold 99,727 Edgewise Therapeutics shares in Q1 2026, an estimated $2.88M.
  • Edgewise Therapeutics made up 3.87% of Siren LLC's portfolio in Q1 2026, its #4 holding.
  • Siren LLC first reported a position in Edgewise Therapeutics in Q3 2024 and has held it in 7 quarters since.
  • 214 funds tracked by Wall St. Rank held Edgewise Therapeutics as of Q1 2026.

Based on Siren LLC's 13F filing for Q1 2026, filed 14 May 2026.