|
1
|
|
$631M
|
–
|
–
|
–
|
|
|
2
|
Paradigm Biocapital Advisors
New York
|
$415M
|
+$98.3M
|
+2,850,417
|
+39%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$341M
|
-$70.2M
|
-2,035,707
|
-20%
|
|
|
4
|
|
$268M
|
+$4.6M
|
+133,345
|
+2%
|
|
|
5
|
|
$247M
|
+$209M
|
+6,075,331
|
New
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$223M
|
+$154M
|
+4,472,083
|
+440%
|
|
|
7
|
Novo Holdings A/S
Hellerup,
Denmark
|
$217M
|
–
|
–
|
–
|
|
|
8
|
Driehaus Capital Management
Chicago,
Illinois
|
$192M
|
+$8.64M
|
+250,681
|
+6%
|
|
|
9
|
Perceptive Advisors
New York
|
$178M
|
-$1.72M
|
-50,000
|
-1%
|
|
|
10
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$157M
|
+$2.5M
|
+72,509
|
+2%
|
|
|
11
|
Baker Bros. Advisors
New York
|
$150M
|
-$99.1M
|
-2,874,221
|
-44%
|
|
|
12
|
Siren LLC
Greenwich,
Connecticut
|
$129M
|
-$42.9M
|
-1,245,634
|
-28%
|
|
|
13
|
Cormorant Asset Management
Boston,
Massachusetts
|
$102M
|
-$25.9M
|
-750,000
|
-23%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$88.3M
|
+$13.2M
|
+384,232
|
+21%
|
|
|
15
|
Integral Health Asset Management
New York
|
$81.3M
|
+$13.8M
|
+400,000
|
+25%
|
|
|
16
|
Braidwell
Stamford,
Connecticut
|
$81.1M
|
-$12.1M
|
-350,618
|
-15%
|
|
|
17
|
|
$79.2M
|
-$10.3M
|
-297,431
|
-13%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$74.3M
|
+$3.83M
|
+111,104
|
+6%
|
|
|
19
|
AllianceBernstein
Nashville,
Tennessee
|
$66.7M
|
+$13.7M
|
+396,855
|
+23%
|
|
|
20
|
MPM BioImpact
Boston,
Massachusetts
|
$65.9M
|
-$1.38M
|
-39,916
|
-2%
|
|
|
21
|
Bank of America
Charlotte,
North Carolina
|
$63.3M
|
+$7.96M
|
+230,900
|
+17%
|
|
|
22
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
$50.9M
|
+$14.7M
|
+426,597
|
+52%
|
|
|
23
|
Dimensional Fund Advisors
Austin,
Texas
|
$46.3M
|
-$2.76M
|
-79,991
|
-7%
|
|
|
24
|
American Century Companies
Kansas City,
Missouri
|
$45.8M
|
-$693K
|
-20,098
|
-2%
|
|
|
25
|
First Light Asset Management
Edina,
Minnesota
|
$44.5M
|
+$3.22M
|
+93,325
|
+9%
|
|
