|
1
|
|
$130M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$76.8M
|
+$5.74M
|
+612,416
|
+8%
|
|
|
3
|
Novo Holdings A/S
Hellerup,
Denmark
|
$54.3M
|
–
|
–
|
–
|
|
|
4
|
Viking Global Investors
Stamford,
Connecticut
|
$39.4M
|
–
|
–
|
–
|
|
|
5
|
Deerfield Management
New York
|
$35.2M
|
–
|
–
|
–
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$31.2M
|
–
|
–
|
–
|
|
|
7
|
Deep Track Capital
Greenwich,
Connecticut
|
$30.2M
|
–
|
–
|
–
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$26.3M
|
-$985K
|
-105,102
|
-3%
|
|
|
9
|
|
$25.7M
|
+$7.11M
|
+758,154
|
+36%
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
$25.4M
|
+$795K
|
+84,795
|
+3%
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$17.7M
|
+$2.17M
|
+231,159
|
+13%
|
|
|
12
|
New Leaf Venture Partners
New York
|
$13.9M
|
–
|
–
|
–
|
|
|
13
|
Janus Henderson Group
London,
|
$12.7M
|
-$1.15M
|
-123,137
|
-8%
|
|
|
14
|
|
$9.52M
|
+$9.4M
|
+1,002,520
|
+1,601%
|
|
|
15
|
DAFNA Capital Management
Los Angeles,
California
|
$6.86M
|
-$134K
|
-14,269
|
-2%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$6.46M
|
+$1.86M
|
+198,624
|
+38%
|
|
|
17
|
Opaleye Management
Boston,
Massachusetts
|
$5.47M
|
-$221K
|
-23,600
|
-4%
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$5.36M
|
+$349K
|
+37,194
|
+7%
|
|
|
19
|
American Century Companies
Kansas City,
Missouri
|
$4.52M
|
+$64K
|
+6,822
|
+1%
|
|
|
20
|
Baker Bros. Advisors
New York
|
$4.47M
|
–
|
–
|
–
|
|
|
21
|
Woodline Partners
San Francisco,
California
|
$3.22M
|
-$1.69M
|
-179,773
|
-33%
|
|
|
22
|
Wellington Management Group
Boston,
Massachusetts
|
$3.05M
|
–
|
–
|
–
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$2.83M
|
+$731K
|
+77,932
|
+33%
|
|
|
24
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$2.66M
|
+$1.01M
|
+108,000
|
+57%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$2.65M
|
+$882K
|
+94,102
|
+46%
|
|
