|
1
|
|
$252M
|
–
|
–
|
–
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$169M
|
+$7.46M
|
+525,804
|
+5%
|
|
|
3
|
Baker Bros. Advisors
New York
|
$119M
|
–
|
–
|
–
|
|
|
4
|
|
$103M
|
-$6.09M
|
-429,559
|
-6%
|
|
|
5
|
Paradigm Biocapital Advisors
New York
|
$100M
|
+$394K
|
+27,787
|
+0.5%
|
|
|
6
|
Novo Holdings A/S
Hellerup,
Denmark
|
$86.8M
|
–
|
–
|
–
|
|
|
7
|
Braidwell
Stamford,
Connecticut
|
$84.5M
|
–
|
–
|
–
|
|
|
8
|
Janus Henderson Group
London,
|
$80.8M
|
-$7.43M
|
-524,018
|
-10%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$77.9M
|
-$533K
|
-37,559
|
-0.8%
|
|
|
10
|
Cormorant Asset Management
Boston,
Massachusetts
|
$65M
|
-$3.43M
|
-241,992
|
-6%
|
|
|
11
|
Siren LLC
Greenwich,
Connecticut
|
$63.2M
|
+$10.5M
|
+736,801
|
+23%
|
|
|
12
|
Perceptive Advisors
New York
|
$61.6M
|
-$12M
|
-844,055
|
-18%
|
|
|
13
|
Bellevue Group
Kuesnacht,
Switzerland
|
$45M
|
–
|
–
|
–
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$36.1M
|
+$1.79M
|
+126,504
|
+6%
|
|
|
15
|
MPM BioImpact
Boston,
Massachusetts
|
$27.9M
|
–
|
–
|
–
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$27.9M
|
-$1.13M
|
-79,574
|
-4%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$27.6M
|
-$1.16M
|
-81,592
|
-5%
|
|
|
18
|
Integral Health Asset Management
New York
|
$24.3M
|
+$7.09M
|
+500,000
|
+50%
|
|
|
19
|
First Light Asset Management
Edina,
Minnesota
|
$23M
|
-$4.24M
|
-299,025
|
-17%
|
|
|
20
|
Dimensional Fund Advisors
Austin,
Texas
|
$19.2M
|
+$1.9M
|
+134,200
|
+13%
|
|
|
21
|
American Century Companies
Kansas City,
Missouri
|
$17.8M
|
+$4.43M
|
+312,307
|
+40%
|
|
|
22
|
New Leaf Venture Partners
New York
|
$16.7M
|
–
|
–
|
–
|
|
|
23
|
|
$14.1M
|
+$2.01M
|
+141,964
|
+20%
|
|
|
24
|
Deerfield Management
New York
|
$12.4M
|
-$18.5M
|
-1,301,626
|
-63%
|
|
|
25
|
Millennium Management
New York
|
$11.8M
|
-$2.79M
|
-196,540
|
-21%
|
|
