|
1
|
|
$401M
|
–
|
–
|
–
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$238M
|
–
|
–
|
–
|
|
|
3
|
|
$171M
|
+$7.52M
|
+377,856
|
+6%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$156M
|
–
|
–
|
–
|
|
|
5
|
Novo Holdings A/S
Hellerup,
Denmark
|
$148M
|
-$15.8M
|
-794,530
|
-13%
|
|
|
6
|
Janus Henderson Group
London,
|
$122M
|
+$38.8M
|
+1,951,220
|
+75%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$121M
|
+$157K
|
+7,897
|
+0.2%
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$90.9M
|
+$7.96M
|
+400,000
|
+13%
|
|
|
9
|
Frazier Life Sciences Management
Palo Alto,
California
|
$75.6M
|
-$17.9M
|
-898,200
|
-24%
|
|
|
10
|
Paradigm Biocapital Advisors
New York
|
$74.4M
|
+$9.22M
|
+463,723
|
+20%
|
|
|
11
|
Perceptive Advisors
New York
|
$62.2M
|
+$9.43M
|
+473,877
|
+26%
|
|
|
12
|
TCG Crossover Management
Palo Alto,
California
|
$56.4M
|
-$3.18M
|
-159,744
|
-7%
|
|
|
13
|
Braidwell
Stamford,
Connecticut
|
$52.3M
|
+$39M
|
+1,958,310
|
New
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$52.1M
|
+$13.8M
|
+693,032
|
+55%
|
|
|
15
|
Deerfield Management
New York
|
$47.5M
|
-$21.8M
|
-1,093,580
|
-38%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$45M
|
+$398K
|
+20,020
|
+1%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$42.7M
|
-$1.45M
|
-73,118
|
-4%
|
|
|
18
|
New Leaf Venture Partners
New York
|
$41.5M
|
–
|
–
|
–
|
|
|
19
|
Viking Global Investors
Stamford,
Connecticut
|
$39.5M
|
–
|
–
|
–
|
|
|
20
|
Bellevue Group
Kuesnacht,
Switzerland
|
$38.1M
|
–
|
–
|
–
|
|
|
21
|
EcoR1 Capital
San Francisco,
California
|
$33.4M
|
–
|
–
|
–
|
|
|
22
|
Deep Track Capital
Greenwich,
Connecticut
|
$29.4M
|
+$18.2M
|
+914,150
|
+490%
|
|
|
23
|
Artisan Partners
Milwaukee,
Wisconsin
|
$26.7M
|
+$19.9M
|
+1,000,632
|
New
|
|
|
24
|
|
$26.7M
|
-$16.3M
|
-818,182
|
-45%
|
|
|
25
|
Millennium Management
New York
|
$26.3M
|
-$3.15M
|
-158,476
|
-14%
|
|
