|
1
|
|
$274M
|
+$7.22M
|
+454,545
|
+3%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$163M
|
+$142M
|
+8,909,091
|
New
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$116M
|
-$2.02M
|
-126,789
|
-2%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$107M
|
+$43.3M
|
+2,727,273
|
+88%
|
|
|
5
|
|
$94.2M
|
+$29.6M
|
+1,859,896
|
+56%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$73.3M
|
+$30.1M
|
+1,892,053
|
+89%
|
|
|
7
|
Viking Global Investors
Stamford,
Connecticut
|
$60.9M
|
-$44.8M
|
-2,820,000
|
-46%
|
|
|
8
|
Frazier Life Sciences Management
Palo Alto,
California
|
$60.3M
|
+$10.1M
|
+636,364
|
+24%
|
|
|
9
|
Cormorant Asset Management
Boston,
Massachusetts
|
$54.8M
|
+$7.22M
|
+454,545
|
+18%
|
|
|
10
|
Deerfield Management
New York
|
$52.4M
|
-$16.8M
|
-1,058,551
|
-27%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$49.6M
|
+$2.12M
|
+133,361
|
+5%
|
|
|
12
|
Paradigm Biocapital Advisors
New York
|
$44.6M
|
+$38.9M
|
+2,446,373
|
New
|
|
|
13
|
Perceptive Advisors
New York
|
$42.3M
|
+$28M
|
+1,764,091
|
+318%
|
|
|
14
|
TCG Crossover Management
Palo Alto,
California
|
$41.5M
|
+$36.1M
|
+2,272,728
|
New
|
|
|
15
|
|
$33.2M
|
+$28.9M
|
+1,818,182
|
New
|
|
|
16
|
Janus Henderson Group
London,
|
$32.9M
|
+$9.38M
|
+590,299
|
+49%
|
|
|
17
|
|
$31.9M
|
+$13.8M
|
+865,948
|
+98%
|
|
|
18
|
New Leaf Venture Partners
New York
|
$28.3M
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$25M
|
+$6.72M
|
+422,851
|
+45%
|
|
|
20
|
Driehaus Capital Management
Chicago,
Illinois
|
$23.1M
|
+$13.9M
|
+872,750
|
+221%
|
|
|
21
|
EcoR1 Capital
San Francisco,
California
|
$22.8M
|
-$35.6M
|
-2,242,809
|
-64%
|
|
|
22
|
State Street
Boston,
Massachusetts
|
$22.1M
|
+$5.07M
|
+318,767
|
+36%
|
|
|
23
|
|
$14.8M
|
+$12.9M
|
+811,718
|
New
|
|
|
24
|
Opaleye Management
Boston,
Massachusetts
|
$12.1M
|
-$540K
|
-34,000
|
-5%
|
|
|
25
|
Parkman Healthcare Partners
Stamford,
Connecticut
|
$11.9M
|
+$32.2K
|
+2,028
|
+0.3%
|
|
