|
1
|
|
$401M
|
–
|
–
|
–
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$238M
|
–
|
–
|
–
|
|
|
3
|
|
$173M
|
+$2.72M
|
+85,448
|
+1%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$164M
|
+$10.1M
|
+315,881
|
+5%
|
|
|
5
|
Novo Holdings A/S
Hellerup,
Denmark
|
$134M
|
-$17.5M
|
-549,900
|
-10%
|
|
|
6
|
Janus Henderson Group
London,
|
$133M
|
+$13.5M
|
+425,421
|
+9%
|
|
|
7
|
Paradigm Biocapital Advisors
New York
|
$120M
|
+$54.3M
|
+1,704,757
|
+61%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$119M
|
-$1.57M
|
-49,214
|
-1%
|
|
|
9
|
Cormorant Asset Management
Boston,
Massachusetts
|
$91M
|
–
|
–
|
–
|
|
|
10
|
Perceptive Advisors
New York
|
$71.7M
|
+$11.3M
|
+355,243
|
+15%
|
|
|
11
|
Braidwell
Stamford,
Connecticut
|
$62.3M
|
+$11.9M
|
+373,886
|
+19%
|
|
|
12
|
Deerfield Management
New York
|
$55.5M
|
+$9.47M
|
+297,503
|
+17%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$45.8M
|
+$969K
|
+30,430
|
+2%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$42.7M
|
+$33K
|
+1,036
|
+0.1%
|
|
|
15
|
Driehaus Capital Management
Chicago,
Illinois
|
$39.9M
|
-$14.6M
|
-459,633
|
-24%
|
|
|
16
|
Bellevue Group
Kuesnacht,
Switzerland
|
$38.2M
|
–
|
–
|
–
|
|
|
17
|
Frazier Life Sciences Management
Palo Alto,
California
|
$33.9M
|
-$49.7M
|
-1,561,622
|
-55%
|
|
|
18
|
Viking Global Investors
Stamford,
Connecticut
|
$32.7M
|
-$8.16M
|
-256,160
|
-17%
|
|
|
19
|
MPM BioImpact
Boston,
Massachusetts
|
$28.8M
|
+$5.16M
|
+162,150
|
+18%
|
|
|
20
|
Artisan Partners
Milwaukee,
Wisconsin
|
$28.6M
|
+$2.26M
|
+70,964
|
+7%
|
|
|
21
|
New Leaf Venture Partners
New York
|
$27.5M
|
-$16.7M
|
-523,500
|
-34%
|
|
|
22
|
Millennium Management
New York
|
$23.7M
|
-$3.12M
|
-98,062
|
-10%
|
|
|
23
|
First Light Asset Management
Edina,
Minnesota
|
$20.8M
|
+$24.9M
|
+780,639
|
New
|
|
|
24
|
American Century Companies
Kansas City,
Missouri
|
$20.6M
|
-$5.22M
|
-164,034
|
-18%
|
|
|
25
|
Siren LLC
Greenwich,
Connecticut
|
$19.6M
|
+$10.5M
|
+330,230
|
+82%
|
|
