|
1
|
|
$143M
|
+$4.9M
|
+484,496
|
+3%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$78.5M
|
+$52.2M
|
+5,161,529
|
+183%
|
|
|
3
|
Novo Holdings A/S
Hellerup,
Denmark
|
$59.7M
|
+$4.9M
|
+484,496
|
+9%
|
|
|
4
|
Viking Global Investors
Stamford,
Connecticut
|
$43.4M
|
+$17M
|
+1,681,897
|
+62%
|
|
|
5
|
Deerfield Management
New York
|
$38.7M
|
–
|
–
|
–
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$34.4M
|
+$11.5M
|
+1,133,386
|
+48%
|
|
|
7
|
Deep Track Capital
Greenwich,
Connecticut
|
$33.2M
|
+$34.1M
|
+3,374,394
|
New
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$30M
|
-$8.06M
|
-798,011
|
-21%
|
|
|
9
|
Citadel Advisors
Miami,
Florida
|
$27.2M
|
+$2.26M
|
+223,706
|
+9%
|
|
|
10
|
|
$20.8M
|
+$625K
|
+61,902
|
+3%
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$17.2M
|
+$5.31M
|
+525,277
|
+43%
|
|
|
12
|
New Leaf Venture Partners
New York
|
$15.3M
|
–
|
–
|
–
|
|
|
13
|
Janus Henderson Group
London,
|
$15.2M
|
-$670K
|
-66,356
|
-4%
|
|
|
14
|
DAFNA Capital Management
Los Angeles,
California
|
$7.69M
|
+$860K
|
+85,153
|
+12%
|
|
|
15
|
Opaleye Management
Boston,
Massachusetts
|
$6.25M
|
+$1.86M
|
+183,600
|
+41%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$5.53M
|
+$380K
|
+37,602
|
+7%
|
|
|
17
|
Woodline Partners
San Francisco,
California
|
$5.31M
|
-$2.34M
|
-231,933
|
-30%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$5.15M
|
+$1.28M
|
+126,691
|
+32%
|
|
|
19
|
Baker Bros. Advisors
New York
|
$4.92M
|
–
|
–
|
–
|
|
|
20
|
American Century Companies
Kansas City,
Missouri
|
$4.91M
|
+$1.96M
|
+194,148
|
+64%
|
|
|
21
|
Wellington Management Group
Boston,
Massachusetts
|
$3.35M
|
–
|
–
|
–
|
|
|
22
|
MPM BioImpact
Boston,
Massachusetts
|
$2.99M
|
+$3.07M
|
+304,027
|
New
|
|
|
23
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$2.52M
|
-$940K
|
-92,985
|
-27%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$2.35M
|
+$219K
|
+21,633
|
+10%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$2M
|
+$884K
|
+87,521
|
+76%
|
|
