|
1
|
|
$112M
|
+$1.04M
|
+138,000
|
+1%
|
|
|
2
|
Novo Holdings A/S
Hellerup,
Denmark
|
$44.5M
|
–
|
–
|
–
|
|
|
3
|
Deerfield Management
New York
|
$31.3M
|
–
|
–
|
–
|
|
|
4
|
Cormorant Asset Management
Boston,
Massachusetts
|
$30.6M
|
-$6.3M
|
-832,874
|
-18%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$22.4M
|
+$2.22M
|
+293,834
|
+12%
|
|
|
6
|
Viking Global Investors
Stamford,
Connecticut
|
$21.7M
|
–
|
–
|
–
|
|
|
7
|
Citadel Advisors
Miami,
Florida
|
$20.2M
|
-$769K
|
-101,782
|
-4%
|
|
|
8
|
EcoR1 Capital
San Francisco,
California
|
$18.8M
|
–
|
–
|
–
|
|
|
9
|
|
$16.3M
|
-$12K
|
-1,592
|
-0.1%
|
|
|
10
|
Janus Henderson Group
London,
|
$12.8M
|
+$1.33M
|
+176,046
|
+12%
|
|
|
11
|
New Leaf Venture Partners
New York
|
$12.4M
|
–
|
–
|
–
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$9.76M
|
+$117K
|
+15,475
|
+1%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$6.14M
|
+$3.11M
|
+411,704
|
+114%
|
|
|
14
|
DAFNA Capital Management
Los Angeles,
California
|
$5.54M
|
+$2.56M
|
+339,209
|
+95%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$4.18M
|
-$298K
|
-39,486
|
-7%
|
|
|
16
|
Baker Bros. Advisors
New York
|
$3.98M
|
–
|
–
|
–
|
|
|
17
|
Opaleye Management
Boston,
Massachusetts
|
$3.59M
|
+$1.12M
|
+148,400
|
+49%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$3.16M
|
-$312K
|
-41,311
|
-9%
|
|
|
19
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$2.78M
|
-$4.17K
|
-552
|
-0.2%
|
|
|
20
|
Wellington Management Group
Boston,
Massachusetts
|
$2.71M
|
–
|
–
|
–
|
|
|
21
|
American Century Companies
Kansas City,
Missouri
|
$2.43M
|
-$1.27K
|
-168
|
-0.1%
|
|
|
22
|
Barclays
London,
United Kingdom
|
$1.75M
|
-$4.93K
|
-652
|
-0.3%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$1.73M
|
-$580K
|
-76,685
|
-26%
|
|
|
24
|
Bank of New York Mellon
New York
|
$1.51M
|
-$179K
|
-23,648
|
-11%
|
|
|
25
|
Logos Global Management
San Francisco,
California
|
$1.19M
|
-$482K
|
-63,744
|
-30%
|
|
