|
1
|
Baker Bros. Advisors
New York
|
$115M
|
+$7.33M
|
+1,090,909
|
+8%
|
|
|
2
|
Janus Henderson Group
London,
|
$93.5M
|
+$7.75M
|
+1,153,978
|
+10%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$70.5M
|
+$15.1M
|
+2,250,000
|
+32%
|
|
|
4
|
|
$66.9M
|
+$6.81M
|
+1,013,905
|
+13%
|
|
|
5
|
Great Point Partners
Greenwich,
Connecticut
|
$60.9M
|
+$3.36M
|
+500,000
|
+7%
|
|
|
6
|
Deerfield Management
New York
|
$52.7M
|
+$5.69M
|
+847,293
|
+14%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$44.2M
|
+$3.29M
|
+490,319
|
+9%
|
|
|
8
|
Jennison Associates
New York
|
$29.4M
|
+$2.54M
|
+378,565
|
+11%
|
|
|
9
|
Fidelity Investments
Boston,
Massachusetts
|
$28.6M
|
-$4.47M
|
-664,828
|
-15%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$25.9M
|
-$1.89M
|
-281,703
|
-8%
|
|
|
11
|
VHCP Management II
New York
|
$24.8M
|
+$5.27M
|
+784,923
|
+32%
|
|
|
12
|
VHCP Management III
New York
|
$23.4M
|
+$20.6M
|
+3,061,091
|
New
|
|
|
13
|
|
$13M
|
+$500K
|
+74,447
|
+5%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$10.3M
|
+$935K
|
+139,272
|
+11%
|
|
|
15
|
Millennium Management
New York
|
$9M
|
-$3.46M
|
-515,526
|
-30%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$8.54M
|
+$776K
|
+115,482
|
+12%
|
|
|
17
|
Eventide Asset Management
Boston,
Massachusetts
|
$7.99M
|
+$7.03M
|
+1,047,000
|
New
|
|
|
18
|
|
$6.79M
|
-$351K
|
-52,203
|
-6%
|
|
|
19
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$5.34M
|
+$3.02M
|
+450,000
|
+180%
|
|
|
20
|
DAFNA Capital Management
Los Angeles,
California
|
$4.97M
|
+$319K
|
+47,434
|
+8%
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$4.7M
|
+$650K
|
+96,843
|
+19%
|
|
|
22
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$4.37M
|
-$290K
|
-43,103
|
-7%
|
|
|
23
|
TIAA CREF Investment Management
New York
|
$3.85M
|
-$223K
|
-33,189
|
-6%
|
|
|
24
|
Ghost Tree Capital
New York
|
$3.81M
|
+$3.36M
|
+500,000
|
New
|
|
|
25
|
Bank of New York Mellon
New York
|
$3.21M
|
+$84.3K
|
+12,544
|
+3%
|
|
