|
1
|
Baker Bros. Advisors
New York
|
$66.8M
|
+$77.1K
|
+15,000
|
+0.1%
|
|
|
2
|
Janus Henderson Group
London,
|
$36.5M
|
+$4.7M
|
+915,419
|
+14%
|
|
|
3
|
Great Point Partners
Greenwich,
Connecticut
|
$35.7M
|
+$14M
|
+2,726,392
|
+57%
|
|
|
4
|
|
$35.7M
|
-$719K
|
-139,861
|
-2%
|
|
|
5
|
Deerfield Management
New York
|
$35.1M
|
+$786K
|
+153,067
|
+2%
|
|
|
6
|
RA Capital Management
Boston,
Massachusetts
|
$33.3M
|
–
|
–
|
–
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$27M
|
-$576K
|
-112,078
|
-2%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$21.5M
|
+$3.14M
|
+610,167
|
+16%
|
|
|
9
|
Fidelity Investments
Boston,
Massachusetts
|
$21.1M
|
+$6.65M
|
+1,293,955
|
+41%
|
|
|
10
|
Jennison Associates
New York
|
$16.7M
|
+$2.17M
|
+422,360
|
+14%
|
|
|
11
|
Millennium Management
New York
|
$12.8M
|
-$5.24M
|
-1,019,287
|
-27%
|
|
|
12
|
VHCP Management II
New York
|
$10.6M
|
-$1.34M
|
-261,148
|
-11%
|
|
|
13
|
Northern Trust
Chicago,
Illinois
|
$5.67M
|
+$67K
|
+13,044
|
+1%
|
|
|
14
|
DAFNA Capital Management
Los Angeles,
California
|
$4.65M
|
-$1.12M
|
-218,576
|
-18%
|
|
|
15
|
|
$4.6M
|
+$128K
|
+24,833
|
+3%
|
|
|
16
|
|
$4.49M
|
-$76.3K
|
-14,842
|
-2%
|
|
|
17
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$4.41M
|
+$578K
|
+112,500
|
+14%
|
|
|
18
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$4.39M
|
+$2.03M
|
+396,068
|
+75%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$4.19M
|
+$299K
|
+58,236
|
+7%
|
|
|
20
|
Renaissance Technologies
New York
|
$3.66M
|
+$1.91M
|
+371,600
|
+94%
|
|
|
21
|
Hudson Bay Capital Management
Stamford,
Connecticut
|
$2.67M
|
+$2.88M
|
+560,000
|
New
|
|
|
22
|
TIAA CREF Investment Management
New York
|
$2.62M
|
-$6.45K
|
-1,255
|
-0.2%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$2.34M
|
-$29.9K
|
-5,816
|
-1%
|
|
|
24
|
Bank of New York Mellon
New York
|
$2.21M
|
-$9.36K
|
-1,821
|
-0.4%
|
|
|
25
|
Citadel Advisors
Miami,
Florida
|
$2.2M
|
+$2.37M
|
+462,079
|
New
|
|
