|
1
|
Baker Bros. Advisors
New York
|
$42.5M
|
+$3.51M
|
+792,755
|
+6%
|
|
|
2
|
VHCP Management II
New York
|
$13.3M
|
+$20.8M
|
+4,689,435
|
New
|
|
|
3
|
|
$11.5M
|
+$6.59M
|
+1,487,851
|
+58%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$9.18M
|
+$1.92M
|
+434,290
|
+15%
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$8.46M
|
-$462K
|
-104,269
|
-3%
|
|
|
6
|
BlackRock Fund Advisors
San Francisco,
California
|
$7.93M
|
+$49.6K
|
+11,202
|
+0.4%
|
|
|
7
|
|
$5.59M
|
-$162K
|
-36,569
|
-2%
|
|
|
8
|
BlackRock Institutional Trust
San Francisco,
California
|
$5.29M
|
+$279K
|
+62,930
|
+3%
|
|
|
9
|
Franklin Resources
San Mateo,
California
|
$4.69M
|
–
|
–
|
–
|
|
|
10
|
Wellington Management Group
Boston,
Massachusetts
|
$4.24M
|
-$26.5M
|
-5,973,580
|
-80%
|
|
|
11
|
Jennison Associates
New York
|
$3.84M
|
+$40.1K
|
+9,041
|
+0.7%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$3.8M
|
-$3.42M
|
-771,436
|
-36%
|
|
|
13
|
|
$3.5M
|
+$688K
|
+155,133
|
+14%
|
|
|
14
|
Cormorant Asset Management
Boston,
Massachusetts
|
$3.06M
|
–
|
–
|
–
|
|
|
15
|
Fidelity Investments
Boston,
Massachusetts
|
$2.83M
|
-$28.8M
|
-6,488,027
|
-87%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$2.41M
|
-$315K
|
-71,123
|
-8%
|
|
|
17
|
|
$1.59M
|
+$2.5M
|
+562,943
|
New
|
|
|
18
|
Spark Investment Management
New York
|
$1.5M
|
+$1.96M
|
+442,500
|
+505%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$1.42M
|
+$112K
|
+25,331
|
+5%
|
|
|
20
|
Tang Capital Management
San Diego,
California
|
$1.22M
|
+$1.91M
|
+430,000
|
New
|
|
|
21
|
|
$1.18M
|
+$1.51M
|
+339,688
|
+432%
|
|
|
22
|
Globeflex Capital
San Diego,
California
|
$1.17M
|
+$1.3M
|
+293,645
|
+244%
|
|
|
23
|
Millennium Management
New York
|
$1.02M
|
+$838K
|
+189,037
|
+109%
|
|
|
24
|
TIAA CREF Investment Management
New York
|
$925K
|
–
|
–
|
–
|
|
|
25
|
Bank of New York Mellon
New York
|
$869K
|
-$79.9K
|
-18,025
|
-6%
|
|
