|
1
|
Baker Bros. Advisors
New York
|
$73.3M
|
+$11.7M
|
+2,280,388
|
+19%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$36.6M
|
+$9.33M
|
+1,822,450
|
+35%
|
|
|
3
|
|
$34.7M
|
+$1.86M
|
+362,803
|
+6%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$31.5M
|
-$3.75K
|
-732
|
-0%
|
|
|
5
|
Deerfield Management
New York
|
$26.1M
|
+$7.56M
|
+1,476,249
|
+42%
|
|
|
6
|
Janus Henderson Group
London,
|
$23.8M
|
+$23.2M
|
+4,534,727
|
New
|
|
|
7
|
Millennium Management
New York
|
$19.7M
|
+$1.79M
|
+350,301
|
+10%
|
|
|
8
|
|
$17.4M
|
-$47.4K
|
-9,253
|
-0.3%
|
|
|
9
|
VHCP Management II
New York
|
$16.6M
|
+$3.53M
|
+690,290
|
+28%
|
|
|
10
|
Fidelity Investments
Boston,
Massachusetts
|
$16.4M
|
–
|
–
|
–
|
|
|
11
|
Jennison Associates
New York
|
$16.1M
|
+$5.1M
|
+995,643
|
+48%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$15.5M
|
-$4.82M
|
-941,428
|
-24%
|
|
|
13
|
Avoro Capital Advisors
New York
|
$9.32M
|
-$896K
|
-175,000
|
-9%
|
|
|
14
|
Great Point Partners
Greenwich,
Connecticut
|
$8.58M
|
+$8.38M
|
+1,637,332
|
New
|
|
|
15
|
|
$7.82M
|
-$3.05M
|
-595,690
|
-29%
|
|
|
16
|
Citadel Advisors
Miami,
Florida
|
$7.31M
|
+$6.35M
|
+1,239,689
|
+795%
|
|
|
17
|
DAFNA Capital Management
Los Angeles,
California
|
$6.25M
|
+$3.08M
|
+602,100
|
+102%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$5.3M
|
+$20.7K
|
+4,035
|
+0.4%
|
|
|
19
|
Acuta Capital Partners
Redwood City,
California
|
$5.22M
|
+$4.24M
|
+827,615
|
+491%
|
|
|
20
|
|
$5.01M
|
-$379
|
-74
|
-0%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$3.92M
|
+$477K
|
+93,166
|
+14%
|
|
|
22
|
|
$3.41M
|
-$1.02M
|
-200,000
|
-24%
|
|
|
23
|
TIAA CREF Investment Management
New York
|
$2.63M
|
+$169K
|
+33,048
|
+7%
|
|
|
24
|
Ghost Tree Capital
New York
|
$2.62M
|
-$896K
|
-175,000
|
-26%
|
|
|
25
|
Alyeska Investment Group
Chicago,
Illinois
|
$2.36M
|
+$2.3M
|
+450,000
|
New
|
|
