|
1
|
Baker Bros. Advisors
New York
|
$80.3M
|
–
|
–
|
–
|
|
|
2
|
Janus Henderson Group
London,
|
$63.6M
|
+$18.9M
|
+3,441,498
|
+45%
|
|
|
3
|
|
$44.4M
|
+$1.55M
|
+281,532
|
+4%
|
|
|
4
|
Great Point Partners
Greenwich,
Connecticut
|
$42.9M
|
–
|
–
|
–
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$40M
|
–
|
–
|
–
|
|
|
6
|
Deerfield Management
New York
|
$34.7M
|
-$7.17M
|
-1,302,964
|
-18%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$30.4M
|
-$1.97M
|
-357,847
|
-6%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$25.3M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$21.1M
|
-$4.55M
|
-827,310
|
-18%
|
|
|
10
|
Jennison Associates
New York
|
$19.9M
|
-$183K
|
-33,157
|
-0.9%
|
|
|
11
|
VHCP Management II
New York
|
$14.1M
|
+$1.34M
|
+243,270
|
+11%
|
|
|
12
|
Millennium Management
New York
|
$9.71M
|
-$5.48M
|
-994,922
|
-37%
|
|
|
13
|
|
$9.36M
|
+$3.69M
|
+669,566
|
+69%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$6.96M
|
+$141K
|
+25,685
|
+2%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$5.75M
|
+$693K
|
+125,845
|
+14%
|
|
|
16
|
|
$5.39M
|
-$308
|
-56
|
-0%
|
|
|
17
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$3.53M
|
-$1.68M
|
-305,168
|
-33%
|
|
|
18
|
DAFNA Capital Management
Los Angeles,
California
|
$3.46M
|
-$2.04M
|
-370,000
|
-38%
|
|
|
19
|
TIAA CREF Investment Management
New York
|
$3.08M
|
-$54.2K
|
-9,851
|
-2%
|
|
|
20
|
Charles Schwab
San Francisco,
California
|
$2.98M
|
+$155K
|
+28,084
|
+6%
|
|
|
21
|
Bank of New York Mellon
New York
|
$2.34M
|
-$298K
|
-54,089
|
-12%
|
|
|
22
|
Renaissance Technologies
New York
|
$2.26M
|
-$2.05M
|
-373,222
|
-49%
|
|
|
23
|
Hudson Bay Capital Management
Stamford,
Connecticut
|
$1.72M
|
-$1.43M
|
-260,000
|
-46%
|
|
|
24
|
Teachers Advisors
New York
|
$1.62M
|
+$65.9K
|
+11,967
|
+4%
|
|
|
25
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$1.43M
|
-$3.72M
|
-675,000
|
-73%
|
|
