|
1
|
|
$239M
|
+$11.2M
|
+1,242,048
|
+5%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$158M
|
–
|
–
|
–
|
|
|
3
|
State Street
Boston,
Massachusetts
|
$152M
|
+$27M
|
+2,982,738
|
+24%
|
|
|
4
|
Deerfield Management
New York
|
$151M
|
+$528K
|
+58,403
|
+0.4%
|
|
|
5
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$114M
|
+$2.07M
|
+228,474
|
+2%
|
|
|
6
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$111M
|
-$954K
|
-105,467
|
-0.9%
|
|
|
7
|
TCG Crossover Management
Palo Alto,
California
|
$110M
|
–
|
–
|
–
|
|
|
8
|
Perceptive Advisors
New York
|
$103M
|
+$26M
|
+2,874,855
|
+39%
|
|
|
9
|
|
$95.3M
|
+$86.3M
|
+9,540,764
|
New
|
|
|
10
|
Vestal Point Capital
New York
|
$83M
|
+$11.5M
|
+1,275,000
|
+18%
|
|
|
11
|
Two Sigma Investments
New York
|
$67.8M
|
+$3.46M
|
+382,721
|
+6%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$62.5M
|
+$4.21M
|
+465,270
|
+8%
|
|
|
13
|
Aberdeen Group
Edinburgh,
United Kingdom
|
$53.1M
|
+$2.44M
|
+270,201
|
+5%
|
|
|
14
|
UBS Group
Zurich,
Switzerland
|
$50.8M
|
+$1.21M
|
+134,286
|
+3%
|
|
|
15
|
Bank of America
Charlotte,
North Carolina
|
$48M
|
-$2.63M
|
-290,481
|
-6%
|
|
|
16
|
|
$44.8M
|
+$19.3M
|
+2,134,431
|
+91%
|
|
|
17
|
Frazier Life Sciences Management
Palo Alto,
California
|
$40.1M
|
–
|
–
|
–
|
|
|
18
|
Nuveen
Charlotte,
North Carolina
|
$40.1M
|
+$1.7M
|
+187,974
|
+5%
|
|
|
19
|
Millennium Management
New York
|
$33.9M
|
+$29M
|
+3,207,008
|
+1,708%
|
|
|
20
|
GW&K Investment Management
Boston,
Massachusetts
|
$31.7M
|
-$627K
|
-69,349
|
-2%
|
|
|
21
|
|
$27.6M
|
+$19.4M
|
+2,140,076
|
+344%
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
$27.2M
|
+$254K
|
+28,130
|
+1%
|
|
|
23
|
Fisher Asset Management
Camas,
Washington
|
$26M
|
-$1.17M
|
-129,226
|
-5%
|
|
|
24
|
Renaissance Technologies
New York
|
$25.3M
|
+$15.9M
|
+1,753,300
|
+226%
|
|
|
25
|
Kynam Capital Management
Princeton,
New Jersey
|
$25.2M
|
-$28.6M
|
-3,158,135
|
-56%
|
|
