XT
SEPN

XTX Topco’s Septerna Inc SEPN Stock Holding History

XTX Topco’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$1.82M Buy
54,489
+17,766
+48% +$504K 0.02% 1194
2026
Q1 		$882K Buy
36,723
+13,408
+58% +$352K 0.02% 1519
2025
Q4 		$650K Buy
+23,315
New +$557K 0.02% 1377
2025
Q3 		– Sell
-22,330
Closed -$236K – 3463
2025
Q2 		$236K Sell
22,330
-15,020
-40% -$124K 0.01% 1591
2025
Q1 		$216K Buy
+37,350
New +$426K 0.01% 1650

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

XTX Topco's SEPN Position: Q2 2026 in Review

XTX Topco increased its Septerna Inc (SEPN) stake by 48% in Q2 2026, buying an estimated $504K and bringing the position to 54,489 shares worth $1.82M. The position accounts for 0.02% of the portfolio, ranked #1194.

XTX Topco first reported a position in SEPN in Q1 2025 and has held it in 5 quarters since. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • XTX Topco held 54,489 shares of Septerna Inc worth $1.82M as of Q2 2026.
  • XTX Topco bought 17,766 Septerna Inc shares in Q2 2026, an estimated $504K.
  • Septerna Inc made up 0.02% of XTX Topco's portfolio in Q2 2026, its #1194 holding.
  • XTX Topco first reported a position in Septerna Inc in Q1 2025 and has held it in 5 quarters since.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on XTX Topco's 13F filing for Q2 2026, filed 14 Aug 2026.