XT
SEPN

XTX Topco’s Septerna Inc SEPN Stock Holding History

XTX Topco’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$882K Buy
36,723
+13,408
+58% +$352K 0.02% 1519
2025
Q4 		$650K Buy
+23,315
New +$557K 0.02% 1377
2025
Q3 		– Sell
-22,330
Closed -$236K – 3463
2025
Q2 		$236K Sell
22,330
-15,020
-40% -$124K 0.01% 1591
2025
Q1 		$216K Buy
+37,350
New +$426K 0.01% 1650

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $401M AUM 284.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $136M AUM 328.39% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $3.61B AUM 203.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

XTX Topco's SEPN Position: Q1 2026 in Review

XTX Topco increased its Septerna Inc (SEPN) stake by 58% in Q1 2026, buying an estimated $352K and bringing the position to 36,723 shares worth $882K. The position accounts for 0.02% of the portfolio, ranked #1519.

XTX Topco first reported a position in SEPN in Q1 2025 and has held it in 4 quarters since. 124 funds tracked by Wall St. Rank hold SEPN as of Q1 2026.

  • XTX Topco held 36,723 shares of Septerna Inc worth $882K as of Q1 2026.
  • XTX Topco bought 13,408 Septerna Inc shares in Q1 2026, an estimated $352K.
  • Septerna Inc made up 0.02% of XTX Topco's portfolio in Q1 2026, its #1519 holding.
  • XTX Topco first reported a position in Septerna Inc in Q1 2025 and has held it in 4 quarters since.
  • 124 funds tracked by Wall St. Rank held Septerna Inc as of Q1 2026.

Based on XTX Topco's 13F filing for Q1 2026, filed 15 May 2026.