Jane Street
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Jane Street’s Praxis Precision Medicines PRAX Stock Holding History

Jane Street’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$337K Buy
+1,008
New +$319K ﹤0.01% 8953
2025
Q4 		– Sell
-31,687
Closed -$5.9M – 12102
2025
Q3 		$1.68M Buy
31,687
+18,684
+144% +$906K ﹤0.01% 5260
2025
Q2 		$547K Buy
13,003
+3,514
+37% +$134K ﹤0.01% 6754
2025
Q1 		$359K Sell
9,489
-27,655
-74% -$1.73M ﹤0.01% 7502
2024
Q4 		$2.86M Sell
37,144
-1,401
-4% -$101K ﹤0.01% 3532
2024
Q3 		$2.22M Buy
38,545
+6,452
+20% +$349K ﹤0.01% 4258
2024
Q2 		$1.33M Sell
32,093
-14,973
-32% -$708K ﹤0.01% 5224
2024
Q1 		$2.87M Buy
47,066
+36,490
+345% +$1.64M ﹤0.01% 3477
2023
Q4 		$236K Buy
+10,576
New +$190K ﹤0.01% 7984
2023
Q1 		– Sell
-3,852
Closed -$163K – 9732
2022
Q4 		$138K Sell
3,852
-3,041
-44% -$94.8K ﹤0.01% 7915
2022
Q3 		$235K Buy
6,893
+431
+7% +$21.5K ﹤0.01% 7936
2022
Q2 		$238K Buy
+6,462
New +$690K ﹤0.01% 7950

Other funds holding PRAX

JT
Jupiter Topco New York $245B AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $29.1B AUM 60.8% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return

Jane Street's PRAX Position: Q2 2026 in Review

Jane Street opened a new position in Praxis Precision Medicines (PRAX) in Q2 2026: 1,008 shares worth $337K. The stake represents ﹤0.01% of the portfolio and ranks #8953 among its holdings. This is a return to the name: Jane Street previously reported a position in PRAX as recently as Q3 2025.

Jane Street first reported a position in PRAX in Q2 2022 and has held it in 12 quarters since. The position peaked at $2.87M in Q1 2024. 306 funds tracked by Wall St. Rank hold PRAX as of Q2 2026.

  • Jane Street held 1,008 shares of Praxis Precision Medicines worth $337K as of Q2 2026.
  • Praxis Precision Medicines was a new Jane Street position in Q2 2026.
  • Praxis Precision Medicines made up ﹤0.01% of Jane Street's portfolio in Q2 2026, its #8953 holding.
  • Jane Street first reported a position in Praxis Precision Medicines in Q2 2022 and has held it in 12 quarters since.
  • Jane Street's Praxis Precision Medicines position peaked at $2.87M in Q1 2024.
  • 306 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.