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Praxis Precision Medicines
PRAX

111 hedge funds and large institutions have $971M invested in Praxis Precision Medicines in 2024 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 30 increasing their positions, 17 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed

729% more first-time investments, than exits

New positions opened: 58 | Existing positions closed: 7

443% more capital invested

Capital invested by funds: $179M → $971M (+$792M)

200% more funds holding in top 10

Funds holding in top 10: 3 → 9 (+6)

117% more call options, than puts

Call options by funds: $2.95M | Put options by funds: $1.36M

85% more funds holding

Funds holding: 60 → 111 (+51)

76% more repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 17

26.5% more ownership

Funds ownership: 93.73% → 120.24% (+27%)

Holders
111
Holders Change
+51
Holders Change %
+85%
% of All Funds
1.6%
Holding in Top 10
9
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+200%
% of All Funds
0.13%
New
58
Increased
30
Reduced
17
Closed
7
Calls
$2.95M
Puts
$1.36M
Net Calls
+$1.59M
Net Calls Change
+$1.34M

Top Buyers

1
RCM
RA Capital Management
Massachusetts
+$37.2M
2
PA
Perceptive Advisors
New York
+$36.9M
3
CAM
Cormorant Asset Management
Massachusetts
+$30.4M
4
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$29.4M
5
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$24M

Top Sellers

1
Bank of America
Bank of America
North Carolina
-$11.7M
2
PHS
PFM Health Sciences
California
-$8.03M
3
Verition Fund Management
Verition Fund Management
Connecticut
-$7.07M
4
SFM
Sphera Funds Management
Israel
-$6.81M
5
TLP
Tri Locum Partners
New York
-$6.38M
Name Holding Trade Value Shares
Change 		Change in
Stake
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$85M +$29.4M +654,362 +89%
CAM
2
Cormorant Asset Management
Massachusetts
$79.9M +$30.4M +676,655 +107%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$58.2M +$11.7M +261,888 +38%
RCM
4
RA Capital Management
Massachusetts
$50.5M +$37.2M +828,380 New
PA
5
Perceptive Advisors
New York
$50.1M +$36.9M +821,589 New
Vanguard Group
6
Vanguard Group
Pennsylvania
$45.4M +$16.7M +373,131 +101%
VA
7
VR Adviser
New York
$43.1M +$15.8M +352,500 +100%
Verition Fund Management
8
Verition Fund Management
Connecticut
$33.3M -$7.07M -157,592 -22%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$32.7M +$24M +535,999 New
PHS
10
PFM Health Sciences
California
$29.1M -$8.03M -178,943 -27%
O
11
OrbiMed
New York
$28.1M +$20.7M +460,512 New
Fidelity Investments
12
Fidelity Investments
Massachusetts
$27M +$19.9M +442,506 +384,788%
VCIM
13
Velan Capital Investment Management
Georgia
$21.4M +$224K +5,000 +1%
KCM
14
Kingdon Capital Management
New York
$21.4M +$150K +3,335 +1%
5VM
15
5AM Venture Management
California
$20.7M +$15.3M +340,000 New
Janus Henderson Group
16
Janus Henderson Group
United Kingdom
$18.9M +$13.9M +310,059 New
DCM
17
Driehaus Capital Management
Illinois
$16.3M +$12M +266,496 New
OCA
18
Octagon Capital Advisors
New York
$15.9M +$11.7M +260,000 New
LCM
19
Laurion Capital Management
New York
$13.7M +$10.1M +225,000 New
BlackRock
20
BlackRock
New York
$13.5M +$4.27M +95,209 +75%
VPC
21
Vestal Point Capital
New York
$12.8M +$9.42M +210,000 New
CIBC Asset Management
22
CIBC Asset Management
Ontario, Canada
$11.7M +$827K +18,436 +11%
SCM
23
Silverarc Capital Management
Massachusetts
$11.6M -$4.18M -93,285 -33%
SFM
24
Sphera Funds Management
Israel
$10.8M -$6.81M -151,847 -46%
Millennium Management
25
Millennium Management
New York
$10.8M +$6.94M +154,606 +692%
1
2 3 4 5

PRAX Hedge Fund Activity: Q1 2024 in Review

111 of the 6,942 institutional investors tracked by Wall St. Rank reported a position in Praxis Precision Medicines (PRAX) for Q1 2024, worth a combined $971M — up 443% from $179M a quarter earlier.

Buyers outnumbered sellers: 58 funds opened new PRAX positions and 7 closed out — a net gain of 51 holders — while 30 added to existing stakes and 17 trimmed.

The largest buyer was RA Capital Management, opening a new position worth an estimated $37.2M. The largest seller was Bank of America, cutting an estimated $11.7M.

  • 111 institutional investors held Praxis Precision Medicines (PRAX) as of Q1 2024, up from 60 in Q4 2023.
  • Funds reported $971M of Praxis Precision Medicines stock for Q1 2024, up 443% quarter-over-quarter.
  • 58 funds opened new Praxis Precision Medicines positions in Q1 2024 and 7 closed out, a net change of +51 holders.
  • The largest Praxis Precision Medicines buyer in Q1 2024 was RA Capital Management, an estimated $37.2M added.
  • The largest Praxis Precision Medicines seller in Q1 2024 was Bank of America, an estimated $11.7M sold.

Based on aggregated 13F filings for Q1 2024.