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Sphera Funds Management’s Praxis Precision Medicines PRAX Stock Holding History

Sphera Funds Management’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-57,901
Closed -$10.8M – 126
2025
Q3 		$3.07M Sell
57,901
-51,856
-47% -$2.51M 0.65% 50
2025
Q2 		$4.62M Sell
109,757
-30,903
-22% -$1.18M 1.08% 31
2025
Q1 		$5.33M Buy
140,660
+49,077
+54% +$3.06M 1.23% 24
2024
Q4 		$7.05M Sell
91,583
-60,724
-40% -$4.39M 1.27% 24
2024
Q3 		$8.76M Sell
152,307
-131,117
-46% -$7.08M 1.39% 21
2024
Q2 		$11.7M Buy
283,424
+106,285
+60% +$5.02M 1.6% 18
2024
Q1 		$10.8M Sell
177,139
-151,847
-46% -$6.81M 1.52% 22
2023
Q4 		$7.33M Buy
328,986
+5,632
+2% +$101K 1.18% 30
2023
Q3 		$8.29M Sell
323,354
-260,935
-45% -$4.94M 1.51% 16
2023
Q2 		$10.1M Buy
+584,289
New +$8.95M 1.57% 14
2021
Q3 		– Sell
-5,040
Closed -$1.38M – 144
2021
Q2 		$1.38M Buy
+5,040
New +$1.8M 0.09% 115
2021
Q1 		– Sell
-6,667
Closed -$5.5M – 194
2020
Q4 		$5.5M Buy
+6,667
New +$3.89M 0.49% 63

Other funds holding PRAX

Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $23.7B AUM 65.43% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
DM
Deerfield Management New York $8.48B AUM 99.04% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return

Sphera Funds Management's PRAX Position: Q4 2025 in Review

Sphera Funds Management sold out of Praxis Precision Medicines (PRAX) in Q4 2025, closing a stake of 57,901 shares — an estimated $10.8M sold.

Sphera Funds Management first reported a position in PRAX in Q4 2020 and held it in 12 quarters. The position peaked at $11.7M in Q2 2024. 250 funds tracked by Wall St. Rank hold PRAX as of Q4 2025.

  • Sphera Funds Management reported no remaining Praxis Precision Medicines position as of Q4 2025 after selling out during the quarter.
  • Sphera Funds Management sold 57,901 Praxis Precision Medicines shares in Q4 2025, an estimated $10.8M.
  • Sphera Funds Management first reported a position in Praxis Precision Medicines in Q4 2020 and held it in 12 quarters.
  • Sphera Funds Management's Praxis Precision Medicines position peaked at $11.7M in Q2 2024.
  • 250 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q4 2025.

Based on Sphera Funds Management's 13F filing for Q4 2025, filed 17 Feb 2026.