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Praxis Precision Medicines
PRAX

Overview Fund Activity

142 hedge funds and large institutions have $1.02B invested in Praxis Precision Medicines in 2025 Q2 according to their latest regulatory filings, with 25 funds opening new positions, 65 increasing their positions, 34 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
142
Holders Change
-7
Holders Change %
-4.7%
% of All Funds
1.9%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
25
Increased
65
Reduced
34
Closed
32
Calls
$26.3M
Puts
$15.5M
Net Calls
+$10.8M
Net Calls Change
+$15.8M

Top Buyers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
$107M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$40.1M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$61.9M
4
BBA
Baker Bros. Advisors
New York
$29M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
$83M

Top Sellers

1
VA
VR Adviser
New York
$0
2
Capital Research Global Investors
Capital Research Global Investors
California
$0
3
PA
Perceptive Advisors
New York
$31.7M
4
SCM
Soleus Capital Management
Connecticut
$40.7M
5
SCM
Silverarc Capital Management
Massachusetts
$421K
Name Holding Trade Value Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$107M +$43.2M +1,026,969 +68%
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$83M +$9.75M +231,827 +13%
CAM
3
Cormorant Asset Management
Massachusetts
$68.3M -$5.05M -120,000 -7%
BlackRock
4
BlackRock
New York
$66.9M +$7.28M +173,193 +12%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$61.9M +$15.9M +377,350 +34%
Morgan Stanley
6
Morgan Stanley
New York
$51.6M +$533K +12,670 +1%
Vanguard Group
7
Vanguard Group
Pennsylvania
$51.1M +$5.41M +128,624 +12%
SCM
8
Soleus Capital Management
Connecticut
$40.7M -$7.27M -173,000 -15%
Point72 Asset Management
9
Point72 Asset Management
Connecticut
$40.1M +$26.1M +620,541 +186%
PA
10
Perceptive Advisors
New York
$31.7M -$9.59M -227,973 -23%
State Street
11
State Street
Massachusetts
$29.4M -$1.64M -38,946 -5%
BBA
12
Baker Bros. Advisors
New York
$29M +$15.1M +357,955 +108%
DM
13
Deerfield Management
New York
$28.9M +$2.82M +67,000 +11%
Assenagon Asset Management
14
Assenagon Asset Management
Luxembourg
$25.4M +$4.07M +96,898 +19%
DCM
15
Driehaus Capital Management
Illinois
$22.3M +$2.08M +49,390 +10%
Bank of America
16
Bank of America
North Carolina
$19.1M -$307K -7,304 -2%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$19M +$1.42M +33,715 +8%
CIBC Asset Management
18
CIBC Asset Management
Ontario, Canada
$16.3M – – –
Balyasny Asset Management
19
Balyasny Asset Management
Illinois
$15.5M -$1.42M -33,749 -8%
Franklin Resources
20
Franklin Resources
California
$13.2M +$967 +23 +0%
IC
21
Ikarian Capital
Texas
$11.6M +$5.53M +131,448 +90%
Goldman Sachs
22
Goldman Sachs
New York
$9.5M +$2.05M +48,728 +27%
LGM
23
Logos Global Management
California
$9.46M +$9.46M +225,000 New
Aberdeen Group
24
Aberdeen Group
United Kingdom
$9M +$5.3M +126,153 +144%
Northern Trust
25
Northern Trust
Illinois
$8.99M +$2.04M +48,529 +29%
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