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Praxis Precision Medicines
PRAX

60 hedge funds and large institutions have $179M invested in Praxis Precision Medicines in 2023 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 32 increasing their positions, 13 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

25,100% more call options, than puts

Call options by funds: $252K | Put options by funds: $1K

146% more repeat investments, than reductions

Existing positions increased: 32 | Existing positions reduced: 13

87.8% more ownership

Funds ownership: 5.93% → 93.73% (+88%)

9% less capital invested

Capital invested by funds: $196M → $179M (-$16.7M)

19% less funds holding

Funds holding: 74 → 60 (-14)

25% less funds holding in top 10

Funds holding in top 10: 4 → 3 (-1)

58% less first-time investments, than exits

New positions opened: 10 | Existing positions closed: 24

Holders
60
Holders Change
-14
Holders Change %
-18.92%
% of All Funds
0.87%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
10
Increased
32
Reduced
13
Closed
24
Calls
$252K
Puts
$1K
Net Calls
+$251K
Net Calls Change
+$106K

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$2.76M
2
Verition Fund Management
Verition Fund Management
Connecticut
+$1.78M
3
PHS
PFM Health Sciences
California
+$1.11M
4
CIBC Asset Management
CIBC Asset Management
Ontario, Canada
+$939K
5
IC
Ikarian Capital
Texas
+$901K

Top Sellers

1
VVA
Vida Ventures Advisors
Massachusetts
-$2.51M
2
SCM
Soleus Capital Management
Connecticut
-$1.97M
3
TLP
Tri Locum Partners
New York
-$1.35M
4
ACM
Altium Capital Management
New York
-$1.11M
5
SSA
Schonfeld Strategic Advisors
New York
-$1.08M
Name Holding Trade Value Shares
Change 		Change in
Stake
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$16.5M +$2.76M +153,333 +26%
Verition Fund Management
2
Verition Fund Management
Connecticut
$15.7M +$1.78M +99,011 +16%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$15.4M – – –
PHS
4
PFM Health Sciences
California
$14.6M +$1.11M +61,882 +10%
CAM
5
Cormorant Asset Management
Massachusetts
$14.1M +$216 +12 +0%
Vanguard Group
6
Vanguard Group
Pennsylvania
$8.26M -$54 -3 -0%
VA
7
VR Adviser
New York
$7.88M -$18 -1 -0%
KCM
8
Kingdon Capital Management
New York
$7.72M -$36 -2 -0%
VCIM
9
Velan Capital Investment Management
Georgia
$7.7M -$18 -1 -0%
SFM
10
Sphera Funds Management
Israel
$7.33M +$101K +5,632 +2%
ACP
11
Acuta Capital Partners
California
$6.68M +$11.5K +636 +0.2%
SCM
12
Silverarc Capital Management
Massachusetts
$6.32M +$168K +9,313 +3%
Bank of America
13
Bank of America
North Carolina
$6.21M +$14.2K +788 +0.3%
TLP
14
Tri Locum Partners
New York
$5.54M -$1.35M -74,958 -23%
IC
15
Ikarian Capital
Texas
$4.46M +$901K +50,000 +33%
CIBC Asset Management
16
CIBC Asset Management
Ontario, Canada
$3.87M +$939K +52,141 +43%
BBA
17
Baker Bros. Advisors
New York
$2.93M +$112K +6,205 +5%
BlackRock
18
BlackRock
New York
$2.82M +$27.8K +1,546 +1%
Acadian Asset Management
19
Acadian Asset Management
Massachusetts
$2.18M +$43.5K +2,417 +3%
Geode Capital Management
20
Geode Capital Management
Massachusetts
$2.07M +$115K +6,412 +7%
Renaissance Technologies
21
Renaissance Technologies
New York
$1.8M +$282K +15,671 +24%
ABG
22
Ally Bridge Group
New York
$1.57M -$18 -1 -0%
Blackstone Inc
23
Blackstone Inc
New York
$1.57M -$18 -1 -0%
Jacobs Levy Equity Management
24
Jacobs Levy Equity Management
New Jersey
$1.48M +$377K +20,929 +46%
7IH
25
72 Investment Holdings
Connecticut
$1.47M – – –
1
2 3 4

PRAX Hedge Fund Activity: Q4 2023 in Review

60 of the 6,859 institutional investors tracked by Wall St. Rank reported a position in Praxis Precision Medicines (PRAX) for Q4 2023, worth a combined $179M — down 8.5% from $196M a quarter earlier.

Sellers outnumbered buyers: 24 funds closed out of PRAX and 10 opened new positions — a net loss of 14 holders — while 13 trimmed existing stakes and 32 added.

The largest buyer was Adage Capital Partners, adding an estimated $2.76M. The largest seller was Vida Ventures Advisors, exiting entirely with an estimated $2.51M sold.

  • 60 institutional investors held Praxis Precision Medicines (PRAX) as of Q4 2023, down from 74 in Q3 2023.
  • Funds reported $179M of Praxis Precision Medicines stock for Q4 2023, down 8.5% quarter-over-quarter.
  • 10 funds opened new Praxis Precision Medicines positions in Q4 2023 and 24 closed out, a net change of -14 holders.
  • The largest Praxis Precision Medicines buyer in Q4 2023 was Adage Capital Partners, an estimated $2.76M added.
  • The largest Praxis Precision Medicines seller in Q4 2023 was Vida Ventures Advisors, an estimated $2.51M sold.

Based on aggregated 13F filings for Q4 2023.