We are live on ! Find out more
PRAX icon

Praxis Precision Medicines

250 hedge funds and large institutions have $8.69B invested in Praxis Precision Medicines in 2025 Q4 according to their latest regulatory filings, with 115 funds opening new positions, 87 increasing their positions, 44 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

700% more funds holding in top 10

Funds holding in top 10: 324 (+21)

667% more first-time investments, than exits

New positions opened: 115 | Existing positions closed: 15

564% more capital invested

Capital invested by funds: $1.31B → $8.69B (+$7.38B)

98% more repeat investments, than reductions

Existing positions increased: 87 | Existing positions reduced: 44

64% more funds holding

Funds holding: 152250 (+98)

0.66% more ownership

Funds ownership: 117.18%117.84% (+0.66%)

8% less call options, than puts

Call options by funds: $219M | Put options by funds: $238M

Holders
250
Holders Change
+98
Holders Change %
+64.47%
% of All Funds
3.04%
Holding in Top 10
24
Holding in Top 10 Change
+21
Holding in Top 10 Change %
+700%
% of All Funds
0.29%
New
115
Increased
87
Reduced
44
Closed
15
Calls
$219M
Puts
$238M
Net Calls
-$18.3M
Net Calls Change
-$22.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$955M +$88.7M +476,227 +17%
BlackRock
2
BlackRock
New York
$613M +$51.7M +277,420 +15%
PA
3
Perceptive Advisors
New York
$588M +$80.3M +431,432 +28%
Vanguard Group
4
Vanguard Group
Pennsylvania
$431M +$36.1M +193,647 +15%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$400M +$245M +1,315,464 +3,044%
OAG
6
Orbis Allan Gray
Bermuda
$370M +$234M +1,255,162 New
BBA
7
Baker Bros. Advisors
New York
$332M +$81.4M +437,000 +63%
Adage Capital Partners
8
Adage Capital Partners
Massachusetts
$285M -$262M -1,408,772 -59%
CAM
9
Cormorant Asset Management
Massachusetts
$280M -$9.31M -50,000 -5%
DCM
10
Driehaus Capital Management
Illinois
$275M +$80.5M +432,510 +86%
DM
11
Deerfield Management
New York
$266M +$11.6M +62,500 +7%
Morgan Stanley
12
Morgan Stanley
New York
$262M +$45.9M +246,394 +38%
State Street
13
State Street
Massachusetts
$260M -$4.64M -24,893 -3%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$232M -$40.5M -217,503 -22%
Goldman Sachs
15
Goldman Sachs
New York
$211M +$22.9M +123,163 +21%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$166M +$19.6M +105,347 +23%
Barclays
17
Barclays
United Kingdom
$156M +$84.6M +454,114 +593%
Bank of America
18
Bank of America
North Carolina
$154M +$7.43M +39,902 +8%
Point72 Asset Management
19
Point72 Asset Management
Connecticut
$145M -$187M -1,003,640 -67%
Assenagon Asset Management
20
Assenagon Asset Management
Luxembourg
$120M -$185K -992 -0.2%
LGM
21
Logos Global Management
California
$111M +$46.6M +250,000 +200%
RCM
22
RA Capital Management
Massachusetts
$110M +$69.6M +373,787 New
SCM
23
Soleus Capital Management
Connecticut
$107M -$92.4M -496,200 -58%
Franklin Resources
24
Franklin Resources
California
$105M +$7.81M +41,917 +13%
VC
25
Vivo Capital
California
$96.9M +$24.2M +130,000 +65%