Adage Capital Partners
PRAX icon

Adage Capital Partners’s Praxis Precision Medicines PRAX Stock Holding History

Adage Capital Partners’s Portfolio PRAX Stock Details PRAX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$263M Sell
815,739
-149,574
-15% -$46.3M 0.41% 46
2025
Q4 		$285M Sell
965,313
-1,408,772
-59% -$262M 0.43% 35
2025
Q3 		$126M Buy
2,374,085
+399,500
+20% +$19.4M 0.2% 97
2025
Q2 		$83M Buy
1,974,585
+231,827
+13% +$8.83M 0.14% 140
2025
Q1 		$66M Buy
1,742,758
+1,137,748
+188% +$71.1M 0.12% 165
2024
Q4 		$46.6M Sell
605,010
-249,073
-29% -$18M 0.08% 231
2024
Q3 		$49.1M Sell
854,083
-280,000
-25% -$15.1M 0.09% 236
2024
Q2 		$46.9M Sell
1,134,083
-258,945
-19% -$12.2M 0.09% 228
2024
Q1 		$85M Buy
1,393,028
+654,362
+89% +$29.4M 0.16% 129
2023
Q4 		$16.5M Buy
738,666
+153,333
+26% +$2.76M 0.03% 483
2023
Q3 		$15M Buy
585,333
+56,624
+11% +$1.07M 0.03% 474
2023
Q2 		$9.12M Buy
528,709
+400,558
+313% +$6.13M 0.02% 589
2023
Q1 		$1.56M Sell
128,151
-22,252
-15% -$939K ﹤0.01% 781
2022
Q4 		$5.37M Hold
150,403
– – 0.01% 737
2022
Q3 		$5.12M Buy
150,403
+33,334
+28% +$1.66M 0.01% 777
2022
Q2 		$4.3M Buy
117,069
+64,264
+122% +$6.86M 0.01% 814
2022
Q1 		$8.09M Buy
52,805
+6,666
+14% +$1.37M 0.02% 750
2021
Q4 		$13.6M Buy
46,139
+5,334
+13% +$1.56M 0.02% 607
2021
Q3 		$11.3M Buy
40,805
+1,666
+4% +$452K 0.02% 655
2021
Q2 		$10.7M Buy
39,139
+11,667
+42% +$4.18M 0.02% 672
2021
Q1 		$13.5M Hold
27,472
– – 0.03% 584
2020
Q4 		$22.7M Buy
+27,472
New +$16M 0.05% 389

Other funds holding PRAX

Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
OAG
Orbis Allan Gray Hamilton, Bermuda $23.7B AUM 65.43% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
DM
Deerfield Management New York $8.48B AUM 99.04% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
CAM
Cormorant Asset Management Boston, Massachusetts $1.99B AUM 737.95% 1-Year Est. Return

Adage Capital Partners's PRAX Position: Q1 2026 in Review

Adage Capital Partners reduced its Praxis Precision Medicines (PRAX) stake by 15% in Q1 2026, selling an estimated $46.3M and leaving 815,739 shares worth $263M. The position accounts for 0.41% of the portfolio, ranked #46.

Adage Capital Partners first reported a position in PRAX in Q4 2020 and has held it in 22 quarters since. The position peaked at $285M in Q4 2025. 289 funds tracked by Wall St. Rank hold PRAX as of Q1 2026.

  • Adage Capital Partners held 815,739 shares of Praxis Precision Medicines worth $263M as of Q1 2026.
  • Adage Capital Partners sold 149,574 Praxis Precision Medicines shares in Q1 2026, an estimated $46.3M.
  • Praxis Precision Medicines made up 0.41% of Adage Capital Partners's portfolio in Q1 2026, its #46 holding.
  • Adage Capital Partners first reported a position in Praxis Precision Medicines in Q4 2020 and has held it in 22 quarters since.
  • Adage Capital Partners's Praxis Precision Medicines position peaked at $285M in Q4 2025.
  • 289 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q1 2026.

Based on Adage Capital Partners's 13F filing for Q1 2026, filed 15 May 2026.