State Street’s Praxis Precision Medicines PRAX Stock Holding History

State Street’s Portfolio PRAX Stock Details PRAX Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$344M	Buy	1,026,443 +142,205	+16%	+$45M	0.01%	743
2026 Q1	$285M	Buy	884,238 +2,023	+0.2%	+$626K	0.01%	775
2025 Q4	$260M	Sell	882,215 -24,893	-3%	-$4.64M	0.01%	809
2025 Q3	$48.1M	Buy	907,108 +209,015	+30%	+$10.1M	﹤0.01%	1742
2025 Q2	$29.4M	Sell	698,093 -38,946	-5%	-$1.48M	﹤0.01%	1972
2025 Q1	$27.9M	Sell	737,039 -31,616	-4%	-$1.97M	﹤0.01%	1939
2024 Q4	$59.2M	Sell	768,655 -20,969	-3%	-$1.52M	﹤0.01%	1641
2024 Q3	$45.4M	Sell	789,624 -29,518	-4%	-$1.59M	﹤0.01%	1752
2024 Q2	$33.9M	Buy	819,142 +774,634	+1,740%	+$36.6M	﹤0.01%	1855
2024 Q1	$2.72M	Buy	44,508 +13,800	+45%	+$619K	﹤0.01%	3175
2023 Q4	$684K	Buy	30,708 +16,938	+123%	+$305K	﹤0.01%	3571
2023 Q3	$353K	Sell	13,770 -270	-2%	-$5.11K	﹤0.01%	3751
2023 Q2	$242K	Sell	14,040 -50,531	-78%	-$774K	﹤0.01%	3938
2023 Q1	$784K	Buy	64,571 +5,518	+9%	+$233K	﹤0.01%	3605
2022 Q4	$2.11M	Buy	59,053 +696	+1%	+$21.7K	﹤0.01%	3360
2022 Q3	$1.99M	Sell	58,357 -281,554	-83%	-$14M	﹤0.01%	3419
2022 Q2	$12.5M	Buy	339,911 +247,019	+266%	+$26.4M	﹤0.01%	2569
2022 Q1	$14.2M	Buy	92,892 +8,371	+10%	+$1.72M	﹤0.01%	2628
2021 Q4	$25M	Buy	84,521 +50,661	+150%	+$14.9M	﹤0.01%	2316
2021 Q3	$9.39M	Buy	33,860 +10,439	+45%	+$2.83M	﹤0.01%	2920
2021 Q2	$6.42M	Sell	23,421 -25,256	-52%	-$9.04M	﹤0.01%	3125
2021 Q1	$23.9M	Buy	48,677 +37,292	+328%	+$26.5M	﹤0.01%	2255
2020 Q4	$9.4M	Buy	+11,385	New	+$6.65M	﹤0.01%	2664

Other funds holding PRAX

Jupiter Topco New York $245B AUM

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return

BBA

Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return

OAG

Orbis Allan Gray Hamilton, Bermuda $29.1B AUM 60.8% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return

Deerfield Management New York $9.59B AUM 113.36% 1-Year Est. Return

State Street's PRAX Position: Q2 2026 in Review

State Street increased its Praxis Precision Medicines (PRAX) stake by 16% in Q2 2026, buying an estimated $45M and bringing the position to 1,026,443 shares worth $344M. The position accounts for 0.01% of the portfolio, ranked #743.

State Street first reported a position in PRAX in Q4 2020 and has held it in 23 quarters since. 309 funds tracked by Wall St. Rank hold PRAX as of Q2 2026.

State Street held 1,026,443 shares of Praxis Precision Medicines worth $344M as of Q2 2026.
State Street bought 142,205 Praxis Precision Medicines shares in Q2 2026, an estimated $45M.
Praxis Precision Medicines made up 0.01% of State Street's portfolio in Q2 2026, its #743 holding.
State Street first reported a position in Praxis Precision Medicines in Q4 2020 and has held it in 23 quarters since.
309 funds tracked by Wall St. Rank held Praxis Precision Medicines as of Q2 2026.

Based on State Street's 13F filing for Q2 2026, filed 7 Aug 2026.